公开(公告)号：US20150165069A1

公开(公告)日：2015-06-18

申请号：US14403626

申请日：2013-05-28

Applicant: CAPSUM

Inventor： Nicolas Atrux-Tallau ,  Thomas Delmas ,  Mathieu Goutayer ,  Audrey Royere

IPC: A61K47/48 ,  A61K31/343 ,  A61K47/34

CPC classification number: A61K47/48869 ,  A61K8/14 ,  A61K8/64 ,  A61K8/86 ,  A61K9/1075 ,  A61K31/343 ,  A61K47/34 ,  A61K47/555 ,  A61K47/61 ,  A61K47/66 ,  A61K47/6925 ,  A61K2800/413 ,  A61K2800/57 ,  A61Q19/00 ,  B01J13/02 ,  B82Y30/00

Abstract: This invention concerns a nanoparticle comprising: a core consisting of a lipid phase (L1) or an aqueous phase (A1); at least one surfactant comprising a hydrophilic part and a lipophilic part; an internal membrane surrounding the core; an external membrane surrounding the internal membrane; and at least one targeting ligand comprising a lipophilic part and a hydrophilic part.

Abstract translation: 本发明涉及纳米颗粒，其包含：由脂质相（L1）或水相（A1）组成的核心; 至少一种包含亲水部分和亲油部分的表面活性剂; 围绕芯的内膜; 围绕内膜的外部膜; 和至少一种包含亲油部分和亲水部分的靶向配体。