公开(公告)号：US12128122B2

公开(公告)日：2024-10-29

申请号：US16915695

申请日：2020-06-29

申请人： Krystal Biotech, Inc.

发明人： Suma Krishnan ,  Trevor Parry ,  Pooja Agarwal

IPC分类号： A61K35/763 ,  A61K8/64 ,  A61K8/65 ,  A61K9/00 ,  A61Q19/08

CPC分类号： A61K8/65 ,  A61K8/64 ,  A61Q19/08 ,  A61K2800/86 ,  A61K2800/91 ,  C12N2710/16621 ,  C12N2710/16631

摘要： The present disclosure provides recombinant nucleic acids comprising one or more polynucleotides encoding one or more cosmetic proteins (e.g., one or more human collagen proteins); viruses comprising the recombinant nucleic acids; compositions (e.g., cosmetic formulations) comprising the recombinant nucleic acids and/or viruses; methods of their use; and articles of manufacture or kits thereof.

公开(公告)号：US20240352069A1

公开(公告)日：2024-10-24

申请号：US18682510

申请日：2021-08-12

申请人： SHENZHEN WINKEY TECHNOLOGY CO., LTD.

发明人： Wenfeng DING ,  Wenhao ZHAO ,  Xinlin SUN ,  Xue CHEN ,  Yan PENG ,  Fuyi GUAN

IPC分类号： C07K7/06 ,  A61K8/64 ,  A61K38/00 ,  A61P17/02 ,  A61Q19/08

CPC分类号： C07K7/06 ,  A61K8/64 ,  A61P17/02 ,  A61Q19/08 ,  A61K38/00

摘要： A peptide as represented by general formula (I), a stereoisomer thereof, a mixture of the stereoisomer, or a cosmetically acceptable salt or pharmaceutically acceptable salt thereof, or a cosmetic composition or pharmaceutical composition thereof, and an application thereof for treatment or care of a disorder, an illness, or a disease of the skin or mucosa.

公开(公告)号：US20240336655A1

公开(公告)日：2024-10-10

申请号：US18294623

申请日：2022-08-04

申请人： AJK BIOPHARMACEUTICAL, LLC

发明人： Keykavous PARANG ,  Hamidreza Montazeri ALIABADI ,  Sandeep LOHAN ,  Dindyal MANDAL ,  Rakesh TIWARI ,  Eman MOHAMMED ,  Ryley HALL

IPC分类号： C07K7/08 ,  A01N63/50 ,  A01P13/00 ,  A61K8/64 ,  A61K38/00 ,  A61K48/00 ,  A61Q19/00 ,  C07K7/64 ,  C12N15/87

CPC分类号： C07K7/08 ,  A01N63/50 ,  A01P13/00 ,  A61K8/64 ,  A61K48/0033 ,  A61Q19/00 ,  C07K7/64 ,  C12N15/87 ,  A61K38/00 ,  A61K2800/10

摘要： Disclosed are transfecting agents for delivery of nucleic acids (e.g., DNA, plasmids, oligos, small interfering RNAs [siRNA], small hairpin RNA [shRNA], microRNAs [miRNA], Clustered Regularly Interspaced Short Palindromic Repeats [CRISPR]) or proteins (phosphoproteins, enzymes, antibodies, vaccines) using a peptide-based, pegylated peptide-based, a peptide attached to a lipophilic moiety (lipidated peptides), or lipophilic pegylated peptides to living cells.

公开(公告)号：US12097393B2

公开(公告)日：2024-09-24

申请号：US18199613

申请日：2023-05-19

申请人： MARY KAY INC.

发明人： Dawn Burke-Colvin ,  Michelle Hines ,  David Gan

IPC分类号： A61K36/00 ,  A61K8/34 ,  A61K8/41 ,  A61K8/58 ,  A61K8/64 ,  A61K8/9789 ,  A61Q1/00 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10

CPC分类号： A61Q1/00 ,  A61K8/345 ,  A61K8/41 ,  A61K8/585 ,  A61K8/64 ,  A61K8/9789 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/10 ,  A61K2800/85

摘要： A method of treating skin is disclosed. The method includes topically applying to the skin a composition comprising Lactobacillus ferment, Punica granatum extract, Camellia sinensis leaf extract, Cucumis sativus fruit extract, niacinamide, sodium hyaluronate, glycerin, and butylene glycol, wherein the skin is treated.

公开(公告)号：US20240299466A1

公开(公告)日：2024-09-12

申请号：US18665945

申请日：2024-05-16

申请人： AOBIOME LLC

发明人： Todd Krueger ,  Larry Weiss

IPC分类号： A61K35/74 ,  A61K8/64 ,  A61K8/99 ,  A61K9/00 ,  A61K9/06 ,  A61K9/107 ,  A61K47/02 ,  A61Q19/00

CPC分类号： A61K35/74 ,  A61K8/64 ,  A61K8/99 ,  A61K9/107 ,  A61K47/02 ,  A61Q19/00 ,  A61K9/0019 ,  A61K9/0043 ,  A61K9/0046 ,  A61K9/0048 ,  A61K9/0053 ,  A61K9/06

摘要： Ammonia oxidizing microorganism preparations for delivery to the visual and auditory systems, kits including ammonia oxidizing preparations for delivery to the visual and auditory systems, and devices for administering ammonia oxidizing preparations to the visual and auditory systems are provided. Methods of introducing ammonia oxidizing microorganisms to the eye are provided. Methods of introducing ammonia oxidizing microorganisms to the ear are provided. Methods of treating disorders, including eye disorders, ear disorders, and inflammatory disorders, with ammonia oxidizing microorganism preparations are provided.

公开(公告)号：US12083157B2

公开(公告)日：2024-09-10

申请号：US17441482

申请日：2020-02-21

申请人： Lucas Meyer Cosmetics

发明人： Joan Attia-Vigneau ,  Estelle Loing ,  Magali Borel

IPC分类号： A61K38/16 ,  A61K8/362 ,  A61K8/365 ,  A61K8/64 ,  A61K8/67 ,  A61P17/10 ,  A61Q17/00 ,  A61Q19/00

CPC分类号： A61K38/16 ,  A61K8/362 ,  A61K8/365 ,  A61K8/64 ,  A61K8/671 ,  A61P17/10 ,  A61Q17/005 ,  A61K2800/5426 ,  A61K2800/544

摘要： A method for treating acne vulgaris by administering a polylysine dendrimer or a salt thereof. Methods for the management of blemish- or acne-prone skin are also described. The polylysine dendrimer is used as an active for restoring or rebalancing skin microbiota. The polylysine dendrimer is also used as an active agent for improving or restoring the aspect and the feel of the skin to be treated.

公开(公告)号：US12077780B2

公开(公告)日：2024-09-03

申请号：US17112911

申请日：2020-12-04

申请人： Allergan Sales, LLC

发明人： Patrick Nido

IPC分类号： C12N5/077 ,  A61K8/64 ,  A61K8/97 ,  A61K8/99 ,  A61K35/33 ,  A61Q19/00

CPC分类号： C12N5/0656 ,  A61K8/64 ,  A61K8/97 ,  A61K8/99 ,  A61K35/33 ,  A61Q19/00 ,  C12N2500/02 ,  C12N2500/32 ,  C12N2513/00

摘要： The production and use of extracellular matrix or conditioned medium compositions and more specifically to compositions obtained by culturing cells under hypoxic conditions on a surface in a suitable growth medium.

公开(公告)号：US20240285499A1

公开(公告)日：2024-08-29

申请号：US18434921

申请日：2024-02-07

申请人： InCipirit Tech (Guangzhou) Co., Ltd. ,  cBioMey (Guangzhou) Technology Co., Ltd.

发明人： Dongcui Li ,  Shaohua Ren ,  Haochi Zheng ,  Xiuqun Zuo ,  Zeyu Zhang ,  Naisheng Jiang ,  Ying Luo

IPC分类号： A61K8/63 ,  A61K8/49 ,  A61K8/64 ,  A61Q7/00

CPC分类号： A61K8/63 ,  A61K8/4953 ,  A61K8/64 ,  A61Q7/00 ,  A61K2800/782

摘要： The present invention belongs to the technical field of daily-use chemicals, and discloses a ginsenoside-containing composition, which includes the following components in parts by weight: 0.001-0.05 parts of palmitoyl tetrapeptide-7, 0.001-0.05 parts of blue copper peptide, 0.1-5 parts of ectoin, and 0.05-5 parts of a ginsenoside composition. According to the present invention, excellent fast acting and consistently-increased hair growth, hair loss prevention and hair development effects are achieved through preferred compounding of the ginsenoside composition and multiple polypeptides, etc. Meanwhile, the present invention further provides use of the composition and a daily-use chemical using the composition.

公开(公告)号：US20240279277A1

公开(公告)日：2024-08-22

申请号：US18639253

申请日：2024-04-18

申请人： ANPEP INC.

发明人： Sang Moon KANG ,  Kee Young LEE ,  Kwang Soon CHOI ,  Sang Joo CHA

IPC分类号： C07K5/103 ,  A61K8/64 ,  A61Q19/08

CPC分类号： C07K5/1008 ,  A61K8/64 ,  A61Q19/08

摘要： Disclosed is a novel peptide, which is a highly functional peptide derived from a natural fermentation product exhibiting an anti-wrinkle activity. A tetrapeptide consists of an amino acid sequence of glycine (Gly)-glutamine (Gln)-valine (Val)-serine (Ser) (SEQ ID NO: 1). The peptide is synthesized by utilizing 2-(4-nitrophenyl) sulfonylethoxycarbonyl-amino acid (Nsc-amino acid) as an intermediate. The anti-wrinkle activity is exhibited through the inhibition of elastase. The anti-wrinkle activity is exhibited through collagen synthesis. A method of preventing skin wrinkle, includes applying to a skin a tetrapeptide consisting of an amino acid sequence GQVS (SEQ ID NO: 1).

公开(公告)号：US20240269075A1

公开(公告)日：2024-08-15

申请号：US18567934

申请日：2022-08-24

申请人： LG Chem, Ltd.

发明人： Yunseop Kim ,  Yeji Kim ,  Jee Seon Kim

IPC分类号： A61K9/16 ,  A61K8/02 ,  A61K8/64 ,  A61K8/73

CPC分类号： A61K9/1652 ,  A61K8/0225 ,  A61K8/64 ,  A61K8/735 ,  A61K9/1658 ,  A61K2800/412 ,  A61K2800/413

摘要： A micro carrier comprising polymer micro particles which includes: a polymer matrix containing a biocompatible polymer; and a polypeptide dispersed in the polymer matrix and having a reactive functional group content of 1 mol/103 g or less, a cell composite, medical composition, cosmetic composition, medical articles and cosmetic articles using the same.