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公开(公告)号：US20150190536A1
公开(公告)日：2015-07-09
申请号：US14198457
申请日：2014-03-05
Applicant: CAREFUSION 2200, INC.
CPC classification number: A61L2/0023 , A01N43/40 , A01N47/44 , A01N25/02 , A01N31/02
Abstract: A method for sterilizing an antiseptic solution includes providing a container containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85° C. to about 135° C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and has a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%.
Abstract translation: 消毒溶液灭菌方法包括提供含有防腐溶液的容器，具有初始纯度的防腐溶液，选择灭菌温度为约85℃至约135℃，灭菌时间为约1分钟至约 19小时后，将杀菌溶液加热到选定的灭菌温度，保持所选灭菌时间的温度，并在灭菌时间到期时终止防腐溶液的加热。 在终止加热后，消毒溶液具有消毒后的纯度。 选择灭菌温度和灭菌时间，使得在终止加热后，防腐溶液是无菌的，并且具有至少约92％的灭菌后纯度和从初始纯度到灭菌后的纯度变化百分点 纯度至多约5％。
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公开(公告)号：US20190046669A1
公开(公告)日：2019-02-14
申请号：US16164244
申请日：2018-10-18
Applicant: CAREFUSION 2200, INC.
Inventor： Satish DEGALA , Christopher Matthew MCGINLEY , Kenneth Bruce THURMOND
Abstract: A method for sterilizing an antiseptic solution includes providing a container containing the antiseptic solution, the antiseptic solution having an initial purity, selecting a sterilization temperature from about 85° C. to about 135° C. and an sterilization time from about 1 minute to about 19 hours, heating the antiseptic solution to the selected sterilization temperature, maintaining the temperature for the selected sterilization time, and terminating the heating of the antiseptic solution when the sterilization time expires. After terminating the heating, the antiseptic solution has a post-sterilization purity. The sterilization temperature and the sterilization time are selected such that after terminating the heating, the antiseptic solution is sterile and has a post-sterilization purity of at least about 92% and the percentage point change in purity from the initial purity to the post-sterilization purity is at most about 5%.
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