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公开(公告)号：US20200093744A1
公开(公告)日：2020-03-26
申请号：US16482157
申请日：2018-01-30
Applicant: CASE WESTERN RESERVE UNIVERSITY
Inventor： Rigoberto Advincula , Eric Baer , Pengfei Cao
Abstract: A polymer construct includes at least one extruded degradable polymer layer having a host polymer material and at least one amphiphilic star-shaped polymer miscible with the host polymer material. The star-shaped polymer includes a polymer core and polymer branches extending therefrom to define a shell around the core. A guest agent is loaded on and/or within the core. The polymer construct upon delivery to a site of interest provides controlled and/or sustained release of the guest agent upon degradation of the at least one polymer layer.
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