公开(公告)号：US20150374702A1

公开(公告)日：2015-12-31

申请号：US14769056

申请日：2013-10-04

Applicant: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION

Inventor： Hyo Jeong KUH ,  Jung Ho KIM

IPC: A61K31/522 ,  A61K9/127 ,  A61K31/704 ,  A61K45/06 ,  A61K31/7068

CPC classification number: A61K31/522 ,  A61K9/127 ,  A61K31/704 ,  A61K31/7068 ,  A61K45/06 ,  C07D473/04 ,  A61K2300/00

Abstract: The present invention provides an anticancer adjuvant containing pentoxifylline. Pentoxifylline inhibits a collagen synthesis in tumors and consequently increases the distribution of an anticancer drug or sensitivity of cancer cells, which thus provides an improved anticancer treatment effect.

Abstract translation: 本发明提供含有己酮可可碱的抗癌佐剂。 己酮可可碱抑制肿瘤中的胶原合成，从而增加抗癌药物的分布或癌细胞的敏感性，从而提供改善的抗癌治疗效果。