公开(公告)号：US20240350502A1

公开(公告)日：2024-10-24

申请号：US18760577

申请日：2024-07-01

Applicant: International IP Holdings LLC

Inventor： Manoj Bhargava

IPC: A61K31/522 ,  A23L33/15 ,  A23L33/175 ,  A61K31/185 ,  A61K31/198 ,  A61K31/365 ,  A61K31/455 ,  A61K31/519 ,  A61K31/675 ,  A61K31/7068 ,  A61K31/714

CPC classification number: A61K31/522 ,  A23L33/15 ,  A23L33/175 ,  A61K31/185 ,  A61K31/198 ,  A61K31/365 ,  A61K31/455 ,  A61K31/519 ,  A61K31/675 ,  A61K31/7068 ,  A61K31/714 ,  A23V2002/00

Abstract: The disclosure relates to an edible energy composition that provides physical and mental benefits when ingested. The edible energy composition includes a methylated xanthine, such as caffeine, a choline derivative, and a source of magnesium. The composition may further include two or more of vitamins B6, niacin and B12 and three or more of glucuronolactone, taurine, L-phenylalanine, and N-acetyl-L-tyrosine.

公开(公告)号：US20240350456A1

公开(公告)日：2024-10-24

申请号：US18631821

申请日：2024-04-10

Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY

Inventor： Ronaldo P. Ferraris ,  Nan Gao ,  Wei Vivian Li

IPC: A61K31/4045 ,  A61K31/047 ,  A61K31/132 ,  A61K31/145 ,  A61K31/19 ,  A61K31/194 ,  A61K31/195 ,  A61K31/197 ,  A61K31/198 ,  A61K31/20 ,  A61K31/205 ,  A61K31/216 ,  A61K31/221 ,  A61K31/223 ,  A61K31/40 ,  A61K31/401 ,  A61K31/4015 ,  A61K31/404 ,  A61K31/405 ,  A61K31/4172 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/51 ,  A61K31/513 ,  A61K31/522 ,  A61K31/609 ,  A61K31/66 ,  A61K31/685 ,  A61K31/7012 ,  A61K31/706 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  A61P1/12 ,  C12Q1/6883 ,  G01N33/68

CPC classification number: A61K31/4045 ,  A61K31/047 ,  A61K31/132 ,  A61K31/145 ,  A61K31/19 ,  A61K31/194 ,  A61K31/195 ,  A61K31/197 ,  A61K31/198 ,  A61K31/20 ,  A61K31/205 ,  A61K31/216 ,  A61K31/221 ,  A61K31/223 ,  A61K31/40 ,  A61K31/401 ,  A61K31/4015 ,  A61K31/404 ,  A61K31/405 ,  A61K31/4172 ,  A61K31/4188 ,  A61K31/455 ,  A61K31/51 ,  A61K31/513 ,  A61K31/522 ,  A61K31/609 ,  A61K31/66 ,  A61K31/685 ,  A61K31/7012 ,  A61K31/706 ,  A61K31/7068 ,  A61K31/7072 ,  A61K31/7076 ,  A61K31/708 ,  A61P1/12 ,  C12Q1/6883 ,  G01N33/6893 ,  C12Q2600/158 ,  G01N2800/06

Abstract: Compositions and methods useful for the diagnosis and treatment of leaky gut syndrome and IBD including Crohn's disease are disclosed.

公开(公告)号：US20240299399A1

公开(公告)日：2024-09-12

申请号：US18672051

申请日：2024-05-23

Applicant: Boehringer Ingelheim International GmbH

Inventor： Thomas KLEIN ,  Maximilian von EYNATTEN ,  Michael MARK

IPC: A61K31/522 ,  A61K31/155 ,  A61K31/18 ,  A61K38/28 ,  A61K45/06 ,  C07D473/06

CPC classification number: A61K31/522 ,  A61K31/155 ,  A61K31/18 ,  A61K38/28 ,  A61K45/06 ,  C07D473/06

Abstract: The present invention relates to methods for treating and/or preventing podocytes related disorders and/or nephrotic syndrome comprising the administration of an effective amount of a certain DPP-4 inhibitor, as well as to the use of a certain DPP-4 inhibitor for treating and/or preventing a metabolic disease in a patient with or at risk of podocytes related disorders and/or nephrotic syndrome.

公开(公告)号：US20240299398A1

公开(公告)日：2024-09-12

申请号：US18620393

申请日：2024-03-28

Applicant: AXCESS GLOBAL SCIENCES, LLC

Inventor： Gary MILLET

IPC: A61K31/522 ,  A61K31/047 ,  A61K31/19

CPC classification number: A61K31/522 ,  A61K31/047 ,  A61K31/19

Abstract: Disclosed herein are “paraxanthine-BHB” compositions including a combination of: (1) paraxanthine; (2) a ketone body or ketone body precursor, such as beta-hydroxybutyrate (BHB) salt, BHB ester, BHB acid, acetoacetate salt, acetoacetate ester, acetoacetic acid, 1,3-butanediol, medium chain fatty acid, or ester of medium chain fatty acid; and (3) optionally a dietetically or pharmaceutically acceptable carrier. In some embodiments, the composition may include a short chain fatty acid or ester thereof in addition to or instead of the ketone body or ketone body precursor. The composition can provide enhanced cognitive flexibility, improved sustained attention, improved working memory, and neuroprotection in a mammal. In addition to such improved mental acuity characteristics, the composition can also beneficially increase resting energy expenditure (resting metabolic rate), enhancing fat loss principally through ketosis while promoting muscle formation and maintenance, as well as modulating lethargy/lightheadedness when entering a ketogenic state.

公开(公告)号：US20240277003A1

公开(公告)日：2024-08-22

申请号：US18571254

申请日：2022-06-19

Applicant: Seattle Gummy Company

Inventor： Feng WAN ,  William Brenden Carlson

IPC: A23G3/42 ,  A23G3/36 ,  A23G3/38 ,  A23G3/44 ,  A61K9/68 ,  A61K31/135 ,  A61K31/198 ,  A61K31/4545 ,  A61K31/495 ,  A61K31/522 ,  A61K36/258 ,  A61K36/287 ,  A61K36/355 ,  A61K36/9068

CPC classification number: A23G3/42 ,  A23G3/364 ,  A23G3/38 ,  A23G3/44 ,  A61K9/0058 ,  A61K31/135 ,  A61K31/198 ,  A61K31/4545 ,  A61K31/495 ,  A61K31/522 ,  A61K36/258 ,  A61K36/287 ,  A61K36/355 ,  A61K36/9068

Abstract: A gummy composition, comprising a semi-solid chewable base comprising a gum composition, a gelling composition, and a bonding composition, wherein the gelling composition comprises a protein-based gelling agent, a carbohydrate-based gelling agent, or a combination thereof, wherein the gum composition and the gelling composition have a ratio of not more than 4:1 w/w, and wherein the bonding composition comprises a mono-, di- tri-, or oligosaccharide, a sugar alcohol, or a combination thereof.

公开(公告)号：US20240261336A1

公开(公告)日：2024-08-08

申请号：US18618017

申请日：2024-03-27

Applicant: FIGENE, LLC

Inventor： Pete O'HEERON ,  Thomas Ichim

IPC: A61K35/33 ,  A61K31/522 ,  A61K31/56 ,  A61K45/06

CPC classification number: A61K35/33 ,  A61K31/522 ,  A61K31/56 ,  A61K45/06

Abstract: Embodiments of the disclosure include methods and compositions for treatment of lung disease, including at least chronic obstructive pulmonary disease (COPD). In particular cases, fibroblasts (including activated fibroblasts) and/or exosomes thereof are provided to an individual for the treatment of COPD. In particular cases the fibroblasts are activated and/or express one or more particular markers.

公开(公告)号：US20240252489A1

公开(公告)日：2024-08-01

申请号：US18482856

申请日：2023-10-07

Applicant: Woodward Specialty LLC

Inventor： John D. Hoekman ,  Kelsey H. Satterly ,  Stephen B. Shrewsbury ,  Scott Youmans ,  Christopher Fuller

IPC: A61K31/4985 ,  A61K9/00 ,  A61K31/522 ,  A61K47/26 ,  A61P25/06

CPC classification number: A61K31/4985 ,  A61K9/008 ,  A61K31/522 ,  A61K47/26 ,  A61P25/06

Abstract: Methods are provided for reducing the frequency of migraine attacks in a subject who has frequent migraine headaches with or without aura. The methods comprise intranasally administering to the subject a pharmaceutical composition comprising dihydroergotamine (DHE) or salt thereof on a repeat dose schedule, wherein each intranasal administration is delivered by a manually actuated, propellant-driven, metered-dose administration device, and wherein the schedule is a chronic intermittent schedule in which each of the repeated administrations is performed while the subject is experiencing a migraine headache.

公开(公告)号：US12042475B2

公开(公告)日：2024-07-23

申请号：US17184577

申请日：2021-02-24

Applicant: Darin Bocian

Inventor： Darin Bocian

IPC: A61N5/06 ,  A61B5/055 ,  A61K31/192 ,  A61K31/277 ,  A61K31/522 ,  A61B5/00 ,  A61B8/08 ,  A61N5/067

CPC classification number: A61K31/192 ,  A61B5/055 ,  A61K31/277 ,  A61K31/522 ,  A61N5/0613 ,  A61B5/4041 ,  A61B8/085 ,  A61N5/0622 ,  A61N5/067

Abstract: Systems and methods for treating a fibrous mass associated with a condition such as Morton's neuroma, plantar firbroma, or Achilles tendinopathy are disclosed. According to illustrative implementations, exemplary methods may comprise identifying a location of the fibrous mass and non-surgically delivering electromagnetic energy to the fibrous mass.

公开(公告)号：US20240226058A1

公开(公告)日：2024-07-11

申请号：US18617150

申请日：2024-03-26

Applicant: Cannacraft, Inc.

Inventor： Matthew W. Elmes ,  James P. Pendergast

IPC: A61K31/352 ,  A23D7/005 ,  A23D7/06 ,  A23L2/52 ,  A23L33/00 ,  A23L33/105 ,  A61K9/00 ,  A61K31/05 ,  A61K31/22 ,  A61K31/4045 ,  A61K31/465 ,  A61K31/522 ,  A61K31/5513 ,  A61K45/06 ,  A61K47/18 ,  A61K47/22

CPC classification number: A61K31/352 ,  A23D7/0053 ,  A23D7/06 ,  A23L2/52 ,  A23L33/105 ,  A23L33/40 ,  A61K9/0056 ,  A61K31/05 ,  A61K31/22 ,  A61K31/4045 ,  A61K31/465 ,  A61K31/522 ,  A61K31/5513 ,  A61K45/06 ,  A61K47/183 ,  A61K47/22 ,  A23V2002/00

Abstract: This disclosure provides cannabinoid compositions with improved shelf-life stability, methods of use thereof, and methods of preparation thereof.

公开(公告)号：US20240197605A1

公开(公告)日：2024-06-20

申请号：US18247542

申请日：2021-10-01

Applicant: DR. KURT WOLFF GMBH & CO. KG

Inventor： Erik SCHULZE ZUR WIESCHE ,  Maike BECKER ,  Jörn Michael VÖLKER

IPC: A61K8/49 ,  A61K8/44 ,  A61K31/198 ,  A61K31/522 ,  A61P17/02 ,  A61P17/14 ,  A61Q5/12 ,  A61Q19/00

CPC classification number: A61K8/4953 ,  A61K8/44 ,  A61K31/198 ,  A61K31/522 ,  A61P17/02 ,  A61P17/14 ,  A61Q5/12 ,  A61Q19/00

Abstract: The present invention relates to a composition which, in addition to caffeine, also contains dimethylglycine and/or a salt of dimethylglycine. In addition, the present invention relates to the use (cosmetic and/or medicinal) of this composition for the treatment of hair, scalp and/or skin.