公开(公告)号：US11731948B2

公开(公告)日：2023-08-22

申请号：US17206265

申请日：2021-03-19

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  A23L27/30 ,  C07C235/74

CPC分类号： C07D291/06 ,  A23L27/30 ,  C07C235/74 ,  A23V2002/00

摘要： Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent composition and reacting an acetoacetamide salt with the cyclizing agent in the composition to form a cyclic sulfur trioxide adduct. The contact time is less than 60 minutes. The process also comprises forming from the cyclic sulfur trioxide adduct composition a finished acesulfame potassium composition comprising non-chlorinated, e.g., non-chlorinated, acesulfame potassium and less than 35 wppm 5-halo acesulfame potassium, preferably less than 5 wppm.

公开(公告)号：US20210206734A1

公开(公告)日：2021-07-08

申请号：US17206230

申请日：2021-03-19

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  A23L27/30

摘要： A process for producing acesulfame potassium, the process comprising the steps of providing a cyclizing agent composition comprising a cyclizing agent and a solvent and having an initial temperature, cooling the cyclizing agent composition to form a cooled cyclizing agent composition having a cooled temperature less than 35° C., reacting an acetoacetamide salt with the cyclizing agent in the cooled cyclizing agent composition to form a cyclic sulfur trioxide adduct composition comprising cyclic sulfur trioxide adduct; and, forming from the cyclic sulfur trioxide adduct in the cyclic sulfur trioxide adduct composition the finished acesulfame potassium composition comprising non-chlorinated acesulfame potassium and less than 39 wppm 5-chloro-acesulfame potassium. The cooled temperature is at least 2° C. less than the initial temperature.

公开(公告)号：US10954203B2

公开(公告)日：2021-03-23

申请号：US16984305

申请日：2020-08-04

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  A23L27/30

摘要： Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of providing a crude acesulfame potassium composition comprising acesulfame potassium and acetoacetamide, concentrating the crude acesulfame potassium composition to form a water stream and an intermediate acesulfame potassium composition comprising acesulfame potassium and less than 33 wppm acetoacetamide, and separating the intermediate acesulfame potassium composition to form the finished acesulfame potassium composition comprising acesulfame potassium and less than 33 wppm acetoacetamide. The concentrating step is conducted at a temperature below 90° C. and the separating step is conducted at a temperature at or below 35° C.

公开(公告)号：US10590098B2

公开(公告)日：2020-03-17

申请号：US16273454

申请日：2019-02-12

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D209/06 ,  C07D291/06 ,  A23L27/30 ,  C07C235/74

摘要： Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent composition and reacting an acetoacetamide salt with the cyclizing agent in the composition to form a cyclic sulfur trioxide adduct. The contact time is less than 60 minutes. The process also comprises forming from the cyclic sulfur trioxide adduct composition a finished acesulfame potassium composition comprising non-chlorinated, e.g., non-chlorinated, acesulfame potassium and less than 35 wppm 5-halo acesulfame potassium, preferably less than 5 wppm.

公开(公告)号：US20190169146A1

公开(公告)日：2019-06-06

申请号：US16273454

申请日：2019-02-12

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  C07C235/74 ,  A23L27/30

摘要： Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent composition and reacting an acetoacetamide salt with the cyclizing agent in the composition to form a cyclic sulfur trioxide adduct. The contact time is less than 60 minutes. The process also comprises forming from the cyclic sulfur trioxide adduct composition a finished acesulfame potassium composition comprising non-chlorinated, e.g., non-chlorinated, acesulfame potassium and less than 35 wppm 5-halo acesulfame potassium, preferably less than 5 wppm.

公开(公告)号：US10233163B2

公开(公告)日：2019-03-19

申请号：US16014431

申请日：2018-06-21

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  A23L27/30

摘要： Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of providing a crude acesulfame potassium composition comprising acesulfame potassium and acetoacetamide, concentrating the crude acesulfame potassium composition to form a water stream and an intermediate acesulfame potassium composition comprising acesulfame potassium and less than 33 wppm acetoacetamide, and separating the intermediate acesulfame potassium composition to form the finished acesulfame potassium composition comprising acesulfame potassium and less than 33 wppm acetoacetamide. The concentrating step is conducted at a temperature below 90° C. and the separating step is conducted at a temperature at or below 35° C.

公开(公告)号：US11724993B2

公开(公告)日：2023-08-15

申请号：US17206208

申请日：2021-03-19

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  A23L27/30

CPC分类号： C07D291/06 ,  A23L27/30 ,  A23L27/31 ,  A23V2002/00

摘要： Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of forming a cyclic sulfur trioxide adduct; hydrolyzing the cyclic sulfur trioxide adduct to form an acesulfame-H composition comprising acesulfame-H; neutralizing the acesulfame-H in the acesulfame-H composition to form a crude acesulfame potassium composition comprising acesulfame potassium and less than 2800 wppm acetoacetamide-N-sulfonic acid, wherein the neutralizing step is conducted or maintained at a pH at or below 11.0; and treating the crude acesulfame potassium composition to form the finished acesulfame potassium composition comprising acesulfame potassium and less than 37 wppm acetoacetamide-N-sulfonic acid.

公开(公告)号：US10975047B2

公开(公告)日：2021-04-13

申请号：US16984356

申请日：2020-08-04

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  A23L27/30 ,  C07C235/74

摘要： Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent composition and reacting an acetoacetamide salt with the cyclizing agent in the composition to form a cyclic sulfur trioxide adduct. The contact time is less than 60 minutes. The process also comprises forming from the cyclic sulfur trioxide adduct composition a finished acesulfame potassium composition comprising non-chlorinated, e.g., non-chlorinated, acesulfame potassium and less than 35 wppm 5-halo acesulfame potassium, preferably less than 5 wppm.

公开(公告)号：US10781191B2

公开(公告)日：2020-09-22

申请号：US16684761

申请日：2019-11-15

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D209/06 ,  C07D291/06 ,  A23L27/30 ,  C07C235/74

摘要： Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent composition and reacting an acetoacetamide salt with the cyclizing agent in the composition to form a cyclic sulfur trioxide adduct. The contact time is less than 60 minutes. The process also comprises forming from the cyclic sulfur trioxide adduct composition a finished acesulfame potassium composition comprising non-chlorinated, e.g., non-chlorinated, acesulfame potassium and less than 35 wppm 5-halo acesulfame potassium, preferably less than 5 wppm.

公开(公告)号：US20190169143A1

公开(公告)日：2019-06-06

申请号：US16273358

申请日：2019-02-12

申请人： Celanese International Corporation

发明人： Christoph Mollenkopf ,  Peter Groer ,  Arvind Yadav

IPC分类号： C07D291/06 ,  A23L27/30

摘要： Compositions and processes for producing high purity acesulfame potassium are described. One process comprises the steps of providing a crude acesulfame potassium composition comprising acesulfame potassium and acetoacetamide, concentrating the crude acesulfame potassium composition to form a water stream and an intermediate acesulfame potassium composition comprising acesulfame potassium and less than 33 wppm acetoacetamide, and separating the intermediate acesulfame potassium composition to form the finished acesulfame potassium composition comprising acesulfame potassium and less than 33 wppm acetoacetamide. The concentrating step is conducted at a temperature below 90° C. and the separating step is conducted at a temperature at or below 35° C.