公开(公告)号：US20230119816A1

公开(公告)日：2023-04-20

申请号：US18081476

申请日：2022-12-14

Applicant: CELL CURE NEUROSCIENCES LTD.

Inventor： Nir Netzer ,  Ofer Wiser ,  Bat Shahaf ,  Orit Gamburg ,  Lior Rosenberg Belmaker ,  Dana Hayoun Neeman ,  Osnat Bohana Kashtan

IPC: A01N1/02 ,  A61K9/00 ,  A61K35/30 ,  A61K47/02 ,  A61K47/18 ,  A61K47/20 ,  A61K47/26

Abstract: Presented herein are ready to administer (RTA) retinal pigment epithelium (RPE) cell therapy compositions for the treatment of retinal degenerative diseases and injuries. A method of formulating human RPE cells for administration to a subject directly after thawing and of formulating RPE cell therapy compositions for cryopreservation and administration of the cryopreserved composition to a subject subsequent to thawing are also presented. In another aspect, the RTA composition may be formulated as a thaw and inject (TAI) composition, whereby the composition is administered by injection subsequent to thawing.

公开(公告)号：US20220408719A1

公开(公告)日：2022-12-29

申请号：US17893977

申请日：2022-08-23

Applicant: CELL CURE NEUROSCIENCES LTD.

Inventor： Nir Netzer ,  Ofer Wiser ,  Bat Shahaf ,  Orit Gamburg ,  Lior Rosenberg Belmaker ,  Dana Hayoun Neeman ,  Osnat Bohana Kashtan

IPC: A01N1/02 ,  A61K9/00 ,  A61K35/30 ,  A61K47/02 ,  A61K47/18 ,  A61K47/20 ,  A61K47/26

Abstract: Presented herein are ready to administer (RTA) retinal pigment epithelium (RPE) cell therapy compositions for the treatment of retinal degenerative diseases and injuries. A method of formulating human RPE cells for administration to a subject directly after thawing and of formulating RPE cell therapy compositions for cryopreservation and administration of the cryopreserved composition to a subject subsequent to thawing are also presented. In another aspect, the RTA composition may be formulated as a thaw and inject (TAI) composition, whereby the composition is administered by injection subsequent to thawing.