公开(公告)号：US20230279350A1

公开(公告)日：2023-09-07

申请号：US18016972

申请日：2021-07-30

Applicant: CELLECTIS S.A.

Inventor： André CHOULIKA ,  Laurent POIROT ,  Beatriz ARANDA ORGILLES ,  Philippe DUCHATEAU

IPC: C12N5/0783 ,  C07K16/28 ,  A61P35/00

CPC classification number: C12N5/0636 ,  C07K16/2887 ,  C07K16/2896 ,  A61P35/00 ,  C07K2317/53 ,  C07K2317/565 ,  C07K2319/03

Abstract: The present invention concerns new engineered immune cells expressing two CARs directed against two different targets, polynucleotides for preparing said immune cells, pharmaceutical compositions comprising said immune cells, and the use of said immune cells in the treatment of cancers.