公开(公告)号：US20220290242A1

公开(公告)日：2022-09-15

申请号：US17291407

申请日：2019-11-05

申请人： CENTRE HENRI BECQUEREL ,  UNIVERSITE DE ROUEN-NORMANDIE ,  INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCH MÉDICALE)

发明人： Philippe RUMINY ,  Vinciane MARCHAND ,  Ahmad ABDEL SATER ,  Pierre-Julien VIAILLY ,  Marie Delphine LANIC ,  Fabrice JARDIN ,  Marick LAE ,  Mathieu VIENNOT

IPC分类号： C12Q1/6886

摘要： The invention concerns a method for diagnosing a cancer in a subject, comprising a step of RT-MLPA on a biological sample obtained from the subject, in which the RT-MLPA step is carried out using at least one pair of probes comprising at least one probe chosen among the probes with SEQ ID NO: 1 to 13, and/or the probes with SEQ ID NO: 96 to 99, and/or the probes with SEQ ID NO: 866 to 938, and/or the probes with SEQ ID NO: 940 to 1104, and/or SEQ ID NO: 211 to 1312, and/or the probes with SEQ ID NO: 96 to 99, and/or the probes with SEQ ID NO: 1105 to 1107 and/or the probe with SEQ ID NO: 939 and/or the probes with SEQ ID NO: 1108 to 1123, each of the probes being fused, at at least one end, with a priming sequence, and at least one of the probes of the pair comprising a molecular barcode sequence.