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公开(公告)号:US20140298497A1
公开(公告)日:2014-10-02
申请号:US14355938
申请日:2012-11-02
申请人: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ECOLE NORMALE SUPERIEURE DE CACHAN , MEDIZINISCHE UNIVERSITÄT WIEN
发明人: Michel Arock , Peter Valent , Rosine Saleh , Ghaith Wedeh , Christian Auclair
CPC分类号: A61K49/0008 , C12N5/0642 , G01N33/5008 , G01N33/5047
摘要: The present invention relates to a human mast cell line corresponding to deposit number CNCM I-4551 and also to the lines derived therefrom, in particular the derived lines corresponding respectively to deposit numbers CNCM I-4552 and CNCM I-4553, and to the uses thereof, in particular for screening for compounds of therapeutic interest.
摘要翻译: 本发明涉及对应于存款编号CNCM I-4551的人类肥大细胞系以及与其相关的线,特别是涉及分别对应于保藏号CNCM I-4552和CNCM I-4553的衍生线,以及用于 特别是用于筛选治疗感兴趣的化合物。
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公开(公告)号:US10383955B2
公开(公告)日:2019-08-20
申请号:US14355938
申请日:2012-11-02
申请人: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , ECOLE NORMALE SUPERIEURE DE CACHAN , MEDIZINISCHE UNIVERSITÄT WIEN
发明人: Michel Arock , Peter Valent , Rosine Saleh , Ghaith Wedeh , Christian Auclair
IPC分类号: A61K49/00 , C12N5/0787 , G01N33/50
摘要: The present invention relates to a human mast cell line corresponding to deposit number CNCM I-4551 and also to the lines derived therefrom, in particular the derived lines corresponding respectively to deposit numbers CNCM I-4552 and CNCM I-4553, and to the uses thereof, in particular for screening for compounds of therapeutic interest.
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公开(公告)号:US20180022808A1
公开(公告)日:2018-01-25
申请号:US15550073
申请日:2016-02-10
发明人: Christoph Madritsch , Sabine Flicker , Rudolf Valenta , Elisabeth Gader-Maier , Julia Eckl-Dorna , Verena Niederberger , Katharina Blatt , Peter Valent , Isabella Ellinger
IPC分类号: C07K16/28 , C07K16/16 , C07K16/46 , A61K39/395
CPC分类号: C07K16/2821 , A61K39/395 , C07K16/16 , C07K16/46 , C07K2317/31 , C07K2317/55 , C07K2317/70
摘要: The present invention relates to an antibody construct comprising at least one antigen binding site specific for ICAM1 and at least one antigen binding site specific for at least one allergen.
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