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公开(公告)号:US09656947B2
公开(公告)日:2017-05-23
申请号:US14406065
申请日:2013-06-06
申请人: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) , UNIVERSITE MONTPELLIER 2, SCIENCES ET TECHNIQUES , ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
发明人: Marc Taillefer , Florian Monnier , Anis Tlili , Grégory Danoun
IPC分类号: C07C213/04 , C07C37/20 , C07B37/04 , C07C213/06 , C07C45/68
CPC分类号: C07C213/04 , C07B37/04 , C07C37/20 , C07C45/68 , C07C213/06 , C07C39/21 , C07C217/18 , C07C49/784 , C07C49/84 , C07C49/813 , C07C49/83
摘要: The present invention concerns a process for preparing a compound of formula (I) by reaction between a compound of formula (II) and a compound of formula (III) in the presence of a copper-containing catalyst, a ligand and base. The invention also concerns the implementing of this process for the preparation of building blocks to prepare molecules of interest in particular in the pharmaceutical, agro-chemical fields, etc.
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公开(公告)号:US09861971B2
公开(公告)日:2018-01-09
申请号:US15001235
申请日:2016-01-19
发明人: Marc Taillefer , Ning Xia , Florian Monnier , Anis Tlili
IPC分类号: B01J31/26 , B01J31/30 , B01J31/22 , C07C41/16 , C07C209/62 , C07C231/08 , C07C249/02
CPC分类号: B01J31/26 , B01J31/1805 , B01J31/2204 , B01J31/2208 , B01J31/2234 , B01J31/30 , B01J2231/4205 , B01J2231/4277 , B01J2231/4283 , B01J2231/4288 , B01J2231/4294 , B01J2531/16 , B01J2531/842 , C07B37/04 , C07C41/16 , C07C209/62 , C07C231/08 , C07C249/02 , C07C43/275 , C07C233/07 , C07C211/46 , C07C251/24
摘要: The present invention concerns a process for creating a Carbon-Carbon bond (C—C) or a Carbon-Heteroatom bond (C—HE) by reacting a compound carrying a leaving group with a nucleophilic compound carrying a carbon atom or a heteroatom (HE) that can substitute for the leaving group, creating a C—C or C—HE bond, wherein the reaction takes place in the presence of an effective quantity of a. a catalytic system comprising a ligand and at least a metal-based catalyst, such a metal catalyst being chosen among iron or copper compounds proviso that only a single metal is present.
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