专利检索 ap:("CHIESI FARMACEUTICI S.P.A.") AND inv:"Stephen P. Davanzo" 第 1 页

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发明授权
Preparation of micronized particles of an antimuscarinic compound by hydrodynamic cavitation 有权

公开(公告)号：US09925168B2

公开(公告)日：2018-03-27

申请号：US15409952

申请日：2017-01-19

申请人： CHIESI FARMACEUTICI S.P.A.

发明人： Stephen P. Davanzo , Barry E. Nall , Timothy J. Rouse , Michele Miozzi

IPC分类号： A61K31/40 , A61K9/00 , A61K9/16 , B01J19/00 , B01J19/06 , A61M15/00

CPC分类号： A61K31/40 , A61K9/0075 , A61K9/008 , A61K9/14 , A61K9/145 , A61K9/1694 , A61K9/5084 , A61M15/0065 , B01J19/008 , B01J19/06

摘要： Crystalline micronized particulate of a glycopyrronium salt may be prepared by hydrodynamic cavitation. The resulting drug particles are physically stable with regard to agglomeration and/or aggregation on storage.