公开(公告)号：US20230211009A1

公开(公告)日：2023-07-06

申请号：US18060966

申请日：2022-12-02

申请人： CHINA MEDICAL UNIVERSITY ,  China Medical University Hospital ,  Shine-On Biomedical Co., Ltd.

发明人： Yi-Wen Chen ,  Der-Yang Cho ,  Hsin-Yuan Fang ,  Ming-You Shie ,  Chih-Ming Pan ,  Kai-Wen Kan ,  Cheng-Yu Chen ,  Min-Hua Yu ,  Shao-Chih Chiu

IPC分类号： A61K47/69 ,  C07K16/28 ,  C07K14/705 ,  A61P35/00 ,  C12N5/071

CPC分类号： A61K47/6901 ,  C07K16/2833 ,  C07K14/70596 ,  A61P35/00 ,  C12N5/0686 ,  C07K2319/03 ,  C07K2317/569 ,  C12N2527/00

摘要： A method for producing exosomes in a large-scale by using a cyclic tensile bioreactor to stimulate cells to release exosomes. In addition, the exosome having an anti-HLA-G protein specific for cancer is used as a delivery vehicle to deliver therapeutic agents for treating cancer.