公开(公告)号：US3836654A

公开(公告)日：1974-09-17

申请号：US35042673

申请日：1973-04-12

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： HODGE E

IPC: A61K31/535 ,  A61K27/00

CPC classification number: A61K31/535 ,  A61K31/505

Abstract: A COMPOSITION CONSISTING ESSENTIALLY OF 5-AMINO-1,3-BIS (2-ETHYLHEXYL) - 5 - METHYL-HEXAHYDROPYRIMIDINE AND 2METHYL-2-NITRO-1,3-DIMORPHOLINOPROPANE IN ABOUT A 1:1 RATIO BY WEIGHT. THE COMPOSITION IS USEFUL AS A THERAPEUTIC AGENT WHEN APPLIED TOPICALLY TO THE INFECTED TISSUES OF AN ANIMAL AT A CONCENTRATION OF 1-2% IN A LOTION, CREAM OR OINTMENT.

公开(公告)号：US3808233A

公开(公告)日：1974-04-30

申请号：US29244972

申请日：1972-09-26

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： HODGE E

IPC: C07D313/00 ,  C07D9/00

CPC classification number: C07D313/00 ,  H03F1/02 ,  H03F3/24

Abstract: A METHOD FOR REDUCING ZEARALINONE TO ZERALANOL IN WHICH THE PRODUCT CONTAINS A MAJOR AMOUNT OF THE HIGHMELTING DIASTEREOISOMER AND A MINOR AMOUNT OF THE LOWMELTING DIASTEREOISOMER OF ZEARALANOL IS DISCLOSED. ZEARALENONE IS CATALYTICALLY REDUCED WITH HYDROGEN FOR A TIME SUFFICIENT TO REDUCE THE ZEARALENONE TO ZEARALANOL IN THE PRESENCE OF A PLATINUM CATALYST AND A WEAK ACID HAVING A FIRST ACID IONIZATION CONSTANT OF FROM ABOUT 1X10**4 TO 5X10**1 IN WATER AT ABOUT 25:C. AND SAID ACID NOT BEING ITSELF REDUCED UNDER THE CONDITIONS OF THE ZEARALENONE REDUCTION.

公开(公告)号：US3751431A

公开(公告)日：1973-08-07

申请号：US3751431D

申请日：1970-02-16

Applicant: COMMERCIAL SOLVENTS CORP

Inventor： WEHRMEISTER H ,  HODGE E

IPC: C07D313/00 ,  C07D9/00

CPC classification number: C07D313/00

Abstract: NEW COMPOUNDS ARE PROVIDED AND HAVE THE FORMULA

1-(R-O-),2,3-(-COO-CH(-CH3)-(CH2)3-B-(CH2)5-),4,6-DI(Y-),

5-(R''-O-)BENZENE

WHERE B IS >C=O, >CHOH OR >CH2; R AND R'' CAN BE HYDROGEN, ALKYL, ACYL OR ARALKYL RADICALS; AND Y IS BROMINE. THOSE COMPOUNDS EXHIBIT ANTIBACTERIAL ACTIVITY AND CAN BE USED IN ANIMAL FEED COMPOSITIONS.