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公开(公告)号：US11583847B2
公开(公告)日：2023-02-21
申请号：US16767349
申请日：2018-11-28
申请人： CORNING INCORPORATED
IPC分类号： B01L3/02 , B29C49/04 , B29C49/16 , B29C49/02 , B29C49/20 , B29K23/00 , B29K25/00 , B29K701/10
摘要： Measuring pipettes including integral or encapsulated filters, as well as methods and apparatuses for forming the same, are provided. A filter material (e.g., a discrete element in solid form) or a filter material precursor (e.g., a foamable thermoplastic composition and a blowing agent) to be introduced into a hollow interior of a softened thermoplastic material present within a mold during pipette fabrication. A pipette includes a filter element comprising foamed polymeric material within a mouthpiece region, wherein an outer portion of the filter element is bound to or encapsulated in an inner wall of the mouthpiece region. A filter material precursor may be supplied coaxially with a tubular flow of thermoplastic material into the mold, may be supplied laterally through a mold wall, or may be injected into a molten thermoplastic pipette forming material upstream of an extruder outlet.
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公开(公告)号：US20210001325A1
公开(公告)日：2021-01-07
申请号：US16767324
申请日：2018-11-28
申请人： CORNING INCORPORATED
摘要： A stretch blow molding method may include fabricating a preform (e.g., by molding, optionally while a core pin rotates within a mold cavity), heating the preform to a softening temperature, stretching and thereby elongating at least a portion of the heated preform, blowing the elongated preform with pressurized fluid within a mold cavity, and cooling the resulting pipette. A system for fabricating a stretch blow molded pipette includes a first mold defining a mold cavity for producing a preform. A stretch rod drive unit is configured to move a stretch rod within an interior of the preform to form an elongated preform, and a second mold defines blow molding cavity and a molding surface to contain expansion of the elongated perform when subjected to blowing by supplying pressurized fluid to an interior thereof.
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公开(公告)号：US20180264460A1
公开(公告)日：2018-09-20
申请号：US15986323
申请日：2018-05-22
申请人： Corning Incorporated
IPC分类号： B01L3/02
CPC分类号： B01L3/021 , B01L2200/12 , B01L2300/0681 , B01L2300/0838 , B01L2300/0858 , B01L2300/12 , B01L2300/16 , B29C49/04 , B29D23/001 , B29K2023/12 , B29K2025/06
摘要： A pipette may comprise a length, a longitudinal axis, and an inner curved surface enclosing a space. The pipette may have a tip region having a tip thickness. The tip region may be connected to a body region having a body thickness. The tip thickness may be greater than the body thickness. The body region may be connected to a mouth region having a mouth thickness. The mouth thickness may be greater than the body thickness. The inner curved surface may not contain bumps or ridges either between the tip region and the body region or between the body region and the mouth region. The pipette may be formed by blow molding or vacuum forming.
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公开(公告)号：US11065612B2
公开(公告)日：2021-07-20
申请号：US15986323
申请日：2018-05-22
申请人： Corning Incorporated
摘要： A pipette may comprise a length, a longitudinal axis, and an inner curved surface enclosing a space. The pipette may have a tip region having a tip thickness. The tip region may be connected to a body region having a body thickness. The tip thickness may be greater than the body thickness. The body region may be connected to a mouth region having a mouth thickness. The mouth thickness may be greater than the body thickness. The inner curved surface may not contain bumps or ridges either between the tip region and the body region or between the body region and the mouth region. The pipette may be formed by blow molding or vacuum forming.
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公开(公告)号：US20180161768A1
公开(公告)日：2018-06-14
申请号：US15579760
申请日：2016-06-08
申请人： Corning Incorporated
发明人： John Claude Cadotte Jr , Cristina Carmela Emphasis King , Venu Krishna Pillai , James Mark Seymour , Kimberly Sue Wayman
CPC分类号： B01L3/021 , B01L2200/12 , B01L2300/028 , B01L2300/0832 , B01L2300/12 , C08L25/06 , C08L2203/02 , C08L2205/025
摘要： A serological pipette has an elongated hollow tubular body having an optical transmission of 40 to 70% over a range of 390 to 700 nm. The pipette body is formed from a polymer composition that includes 5 to 30 wt. % poly(styrene-butadiene-styrene) and 70 to 95 wt. % polystyrene. The tubular body is formed by extrusion at a barrel temperature ranging from 400 to 500F.
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公开(公告)号：US20240261777A1
公开(公告)日：2024-08-08
申请号：US18639408
申请日：2024-04-18
申请人： CORNING INCORPORATED
CPC分类号： B01L3/021 , B29C49/06 , B01L2200/12 , B01L2300/028 , B01L2300/0858
摘要： A stretch blow molding method may include fabricating a preform (e.g., by molding, optionally while a core pin rotates within a mold cavity), heating the preform to a softening temperature, stretching and thereby elongating at least a portion of the heated preform, blowing the elongated preform with pressurized fluid within a mold cavity, and cooling the resulting pipette. A system for fabricating a stretch blow molded pipette includes a first mold defining a mold cavity for producing a preform. A stretch rod drive unit is configured to move a stretch rod within an interior of the preform to form an elongated preform, and a second mold defines blow molding cavity and a molding surface to contain expansion of the elongated perform when subjected to blowing by supplying pressurized fluid to an interior thereof.
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公开(公告)号：US20240123439A1
公开(公告)日：2024-04-18
申请号：US18279059
申请日：2022-02-18
申请人： CORNING INCORPORATED
发明人： Shinu Baby , Daniel Warren Hawtof , Michael Kurt Schaefer , Mark Henry Seibel , James Mark Seymour
IPC分类号： B01L3/02
CPC分类号： B01L3/021 , B01L2300/0681
摘要： A stretch blow molded pipette is provided that includes a tubular body arranged between a tip region and a mouthpiece region. The tip region has an average wall thickness that is greater than a wall thickness of the tubular body, and the body region has an average wall thickness of less than 0.032 inches (in) and a hoop strength of at least 15 pound-feet (lbf).
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公开(公告)号：US20200330975A1
公开(公告)日：2020-10-22
申请号：US16766058
申请日：2018-11-28
申请人： CORNING INCORPORATED
摘要： Unitary measuring pipettes include a tubular body of biaxially oriented thermoplastic material, together with size reduction, elimination, and/or reorientation of longitudinally spaced, raised circumferential witness features, to mitigate or avoid interference between such witness features and graduated volumetric markings on an outside surface of the tubular body. Methods and apparatus for vacuum forming of unitary measuring pipettes are also provided. Gas permeable apertures or pores having a maximum width of no greater than 150 microns, in ranges of 10-100 microns, 10-50 microns, or subranges thereof, may be defined in face plates or inserts received by mold blanks, or defined in molding surface of cooperating mold bodies, and may be used to produce a tubular pipette body having reduced height witness features. Cooperating mold bodies may each be produced from multiple mold body sections with gas passages defined therein and/or therebetween.
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公开(公告)号：US20200164564A1
公开(公告)日：2020-05-28
申请号：US16612964
申请日：2018-05-21
申请人： CORNING INCORPORATED
摘要： A method for producing pipettes (110, 111, 112) is provided. The method includes extruding a polymer melt into at least one mold segment of a mold assembly (120) having a plurality of mold segments to form a parison (50) or preform, wherein the plurality of mold segments (122) comprise cavities (42) that are shaped to form pipettes when in communication with the cavity of an adjacent mold segment; forming at least two pipettes in the shape of the mold segment cavities by blow-molding or vacuum forming the parison or preform, each of the at least two pipettes having proximal and distal ends; heating the pipettes to form a locally heated portion of the at least two pipettes; and separating the pipettes by cutting the locally heated portion of the at least two pipettes with separation feature (64, 66, 194, 196).
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公开(公告)号：US11986817B2
公开(公告)日：2024-05-21
申请号：US16767324
申请日：2018-11-28
申请人： CORNING INCORPORATED
CPC分类号： B01L3/021 , B29C49/06 , B01L2200/12 , B01L2300/028 , B01L2300/0858
摘要： A stretch blow molding method may include fabricating a preform (e.g., by molding, optionally while a core pin rotates within a mold cavity), heating the preform to a softening temperature, stretching and thereby elongating at least a portion of the heated preform, blowing the elongated preform with pressurized fluid within a mold cavity, and cooling the resulting pipette. A system for fabricating a stretch blow molded pipette includes a first mold defining a mold cavity for producing a preform. A stretch rod drive unit is configured to move a stretch rod within an interior of the preform to form an elongated preform, and a second mold defines blow molding cavity and a molding surface to contain expansion of the elongated perform when subjected to blowing by supplying pressurized fluid to an interior thereof.
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