公开(公告)号：US20140220649A1

公开(公告)日：2014-08-07

申请号：US14245907

申请日：2014-04-04

Applicant: COSKATA, INC.

Inventor： Richard E. Tobey ,  Toby D. Allen ,  Peter Martin Lokken ,  Andrew James Heinen ,  Gengsheng Chen

IPC: C12P7/16

CPC classification number: C12P7/16 ,  C12P7/40 ,  Y02E50/10

Abstract: The invention relates to improvements in the production of butanol and butyrate by microbial fermentation, particularly to production of alcohols by microbial fermentation of a substrate comprising CO and the addition of an inorganic sulfur additive. It more particularly relates to the provision of an inorganic organic sulfur source to a fermentation system such that one or more micro-organisms convert a substrate comprising CO to butanol. In one aspect the invention uses a sulfur additive comprising inorganic sulfur compounds having a +2 to a +4 sulfur oxidation state that produces sulfur oxoanions and hydrosulfur oxoanions in an aqueous fermentation medium.

Abstract translation: 本发明涉及通过微生物发酵生产丁醇和丁酸酯的方法的改进，特别是通过微生物发酵包含CO和添加无机硫添加剂的基质来生产醇。 更特别地涉及向发酵系统提供无机有机硫源，使得一种或多种微生物将包含CO的底物转化为丁醇。 在一个方面，本发明使用包含在含水发酵培养基中产生硫氧代阴离子和硫代氧代阴离子的具有+2至+4硫氧化态的无机硫化合物的硫添加剂。