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公开(公告)号:US20220274917A1
公开(公告)日:2022-09-01
申请号:US17753239
申请日:2020-09-04
Inventor: Amol Arvind KULKARNI , Brijesh SHARMA
IPC: C07C277/08
Abstract: The present invention provides a continuous solvent free and additive free process for the synthesis of Metformin Hydrochloride in a screw reactor. >90% conversion of the solid substrates without solvent is obtained in a screw reactor to produce Metformin Hydrochloride with at least 90% selectivity.
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公开(公告)号:US20220410116A1
公开(公告)日:2022-12-29
申请号:US17756638
申请日:2020-11-27
Inventor: Amol Arvind KULKARNI , Mrityunjay Keshavprasad SHARMA
IPC: B01J19/24 , B01F25/421 , B01F23/50 , B01F35/92 , B01J4/00
Abstract: A continuous flow reactor without any moving parts to facilitate solid-liquid reaction without clogging is disclosed herein. It comprises plurality of identical cavities in series/sequence, each cavity being provided with: a pair of inlets at the top to allow entry of reactants into the reactor; an outlet at the bottom to allow the reactants to the next cavity for mixing; and a jacket covering around the cavities to provide heating or cooling effect as per the requirement. The outlet of the previous cavity is inclined at a suitable angle relative to the outlet of the next cavity to prevent clogging and facilitate efficient mixing of the reactants.
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3.
公开(公告)号:US20220389226A1
公开(公告)日:2022-12-08
申请号:US17776870
申请日:2020-11-16
Inventor: Amol Arvind KULKARNI , Chinmay Abhay SHUKLA
Abstract: The present disclosure provides a continuous process for the synthesis coupled compounds of diazonium salts including azo dyes involving in-situ generation of diazonium salts. It further discloses a set up to carry out the process for the synthesis of coupled compounds of diazonium salts.
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4.
公开(公告)号:US20220388062A1
公开(公告)日:2022-12-08
申请号:US17756037
申请日:2020-11-12
Inventor: Amol Arvind KULKARNI , Prachi KATE , Suneha PATIL
Abstract: A continuous flow process for the synthesis of metal nanowires using a bubble column reactor. Also disclosed are different types of multiphase bubble column reactors for synthesizing metal nanowires in high yields and purity through a continuous process. The continuous process provides tunability for the aspect ratio of the nanowires.
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公开(公告)号:US20210060656A1
公开(公告)日:2021-03-04
申请号:US16644597
申请日:2018-09-06
Inventor: Amol Arvind KULKARNI , Jaydeep Bipin DESHPANDE , Prachi Ashok KATE
Abstract: The present invention disclosed an efficient, continuous flow process for the synthesis metal nanowires by using a continuous stirred tank reactor (CSTRs) in series for varying the aspect ratio of metal nanowires and nanorods formed by feeding affixed quantities of metal salt and polymeric surfactant with a reducing solvent like glycol to an axially mixed reactor.
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