公开(公告)号：US20210307819A1

公开(公告)日：2021-10-07

申请号：US17349301

申请日：2021-06-16

申请人： CREO MEDICAL LIMITED

发明人： Christopher HANCOCK ,  Steven MORRIS ,  Patrick BURN ,  Louis TURNER ,  George ULLRICH ,  David WEBB

IPC分类号： A61B18/14 ,  A61B18/18 ,  H01P1/06 ,  A61B18/12

摘要： Electrical instrument for applying radiofrequency and/or microwave frequency energy to tissue, comprising: a distal part comprising an instrument tip for applying radiofrequency and/or microwave frequency energy to tissue, the instrument tip comprising first and second conductive elements; a coaxial feed cable comprising an inner conductor, a tubular outer conductor coaxial with the inner conductor, and dielectric material separating the inner and outer conductors, the coaxial feed cable being for conveying radiofrequency and/or microwave frequency energy to the distal part; wherein: the inner conductor is electrically connected to the first conductive element and the outer conductor is electrically connected to the second conductive element through a rotatable connection between the distal part and the coaxial feed cable that allows rotation of the distal part relative to the coaxial feed cable; and the instrument comprises an actuator for rotating the distal part in a first rotational direction relative to the feed cable.

公开(公告)号：US20190110837A1

公开(公告)日：2019-04-18

申请号：US16089586

申请日：2017-05-30

申请人： CREO MEDICAL LIMITED

发明人： Simon MEADOWCROFT ,  Christopher Paul HANCOCK ,  George ULLRICH ,  David WEBB ,  Louis TURNER ,  Julian Mark EBBUTT

IPC分类号： A61B18/18

摘要： An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.

公开(公告)号：US20220008129A1

公开(公告)日：2022-01-13

申请号：US17294637

申请日：2019-11-28

申请人： CREO MEDICAL LIMITED

发明人： Christopher Paul HANCOCK ,  William TAPLIN ,  George ULLRICH ,  Shaun PRESTON

IPC分类号： A61B18/18

摘要： An electrosurgical instrument having a radiating tip portion capable performing tissue ablation using microwave energy and electroporation (e.g. non-thermal irreversible electroporation) in a minimally invasive manner. The electrosurgical instrument may be used to perform microwave ablation and electroporation separately (e.g. sequentially) or simultaneously. The radiating tip portion may be dimensioned to be suitable for insertion into a pancreas via a surgical scoping device, to provide a rapid and accurate alternative to known RF ablation techniques. By enabling tumours within the pancreas to be treated using a minimally invasive procedure, it may be a viable option to use ablation and/or electroporation treatment for both curative as well as palliative reasons.

公开(公告)号：US20210307822A1

公开(公告)日：2021-10-07

申请号：US17349483

申请日：2021-06-16

申请人： CREO MEDICAL LIMITED

发明人： Christopher HANCOCK ,  Steven MORRIS ,  Patrick BURN ,  Louis TURNER ,  George ULLRICH ,  David WEBB

IPC分类号： A61B18/14 ,  A61B18/18 ,  H01P1/06 ,  A61B18/12

摘要： Electrical instrument for applying radiofrequency and/or microwave frequency energy to tissue, comprising: a distal part comprising an instrument tip for applying radiofrequency and/or microwave frequency energy to tissue, the instrument tip comprising first and second conductive elements; a coaxial feed cable comprising an inner conductor, a tubular outer conductor coaxial with the inner conductor, and dielectric material separating the inner and outer conductors, the coaxial feed cable being for conveying radiofrequency and/or microwave frequency energy to the distal part; wherein: the inner conductor is electrically connected to the first conductive element and the outer conductor is electrically connected to the second conductive element through a rotatable connection between the distal part and the coaxial feed cable that allows rotation of the distal part relative to the coaxial feed cable; and the instrument comprises an actuator for rotating the distal part in a first rotational direction relative to the feed cable.

公开(公告)号：US20210307820A1

公开(公告)日：2021-10-07

申请号：US17349356

申请日：2021-06-16

申请人： CREO MEDICAL LIMITED

发明人： Christopher HANCOCK ,  Steven MORRIS ,  Patrick BURN ,  Louis TURNER ,  George ULLRICH ,  David WEBB

IPC分类号： A61B18/14 ,  A61B18/18 ,  H01P1/06 ,  A61B18/12

摘要： Electrical instrument for applying radiofrequency and/or microwave frequency energy to tissue, comprising: a distal part comprising an instrument tip for applying radiofrequency and/or microwave frequency energy to tissue, the instrument tip comprising first and second conductive elements; a coaxial feed cable comprising an inner conductor, a tubular outer conductor coaxial with the inner conductor, and dielectric material separating the inner and outer conductors, the coaxial feed cable being for conveying radiofrequency and/or microwave frequency energy to the distal part; wherein: the inner conductor is electrically connected to the first conductive element and the outer conductor is electrically connected to the second conductive element through a rotatable connection between the distal part and the coaxial feed cable that allows rotation of the distal part relative to the coaxial feed cable; and the instrument comprises an actuator for rotating the distal part in a first rotational direction relative to the feed cable.

公开(公告)号：US20230165986A1

公开(公告)日：2023-06-01

申请号：US17997409

申请日：2021-04-29

申请人： CREO MEDICAL LIMITED

发明人： Christopher Paul HANCOCK ,  George ULLRICH ,  David Edward WEBB ,  Louis TURNER ,  George HODGKINS ,  Shaun PRESTON ,  Simon MEADOWCROFT

IPC分类号： A61L2/14 ,  A61L2/18 ,  A61L2/26

CPC分类号： A61L2/14 ,  A61L2/18 ,  A61L2/26 ,  A61L2202/11

摘要： Sterilization systems suitable for clinical use, comprising: a housing defining a water mist fluid flow path between an inlet for receiving water mist and an outlet for directing a flow of hydroxyl radicals towards a region to be sterilised; an energy delivery tip configured to produce a thermal or non-thermal plasma; a coaxial transmission line arranged to convey radiofrequency (RF) and/or microwave frequency electromagnetic (EM) energy; and a gas conduit in the housing and arranged to deliver gas to the energy delivery tip, wherein the energy delivery tip extends from a distal end of the coaxial transmission line. The energy delivery tip comprises: a first electrode; and a second electrode. The first electrode and second electrode are configured to: strike a plasma in the gas delivered to the energy delivery tip, and direct the plasma into the water mist fluid flow path to form hydroxyl radicals therein.

公开(公告)号：US20230118398A1

公开(公告)日：2023-04-20

申请号：US18068125

申请日：2022-12-19

申请人： CREO MEDICAL LIMITED

发明人： Simon MEADOWCROFT ,  Christopher Paul HANCOCK ,  George ULLRICH ,  David WEBB ,  Louis TURNER ,  Julian Mark EBBUTT

IPC分类号： A61B18/18 ,  A61B18/14

摘要： An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.

公开(公告)号：US20220202490A1

公开(公告)日：2022-06-30

申请号：US17594510

申请日：2020-04-28

申请人： Creo Medical Limited

发明人： Christopher HANCOCK ,  Shaun PRESTON ,  William TAPLIN ,  Sandra SWAIN ,  George ULLRICH ,  David WEBB

IPC分类号： A61B18/18

摘要： An electrosurgical system for treating biological tissue that comprises: an electrosurgical generator to supply microwave energy; a surgical scoping device having a steerable insertion cord for insertion to a treatment site; and an electrosurgical instrument dimensioned to fit within an instrument channel that is located within the insertion cord. The electrosurgical instrument comprises: a flexible coaxial cable arranged to convey the microwave energy; and a radiating tip portion connected at an end of the coaxial cable and configured to receive microwave energy. The radiating tip portion comprises: a coaxial transmission line for conveying the microwave energy; and a needle tip mounted at an end of the proximal coaxial transmission line, wherein the electrosurgical instrument is slidable within the instrument channel to extend the needle tip beyond an end of the instrument channel to puncture biological tissue; the needle tip is arranged to deliver the microwave energy into biological tissue.

公开(公告)号：US20210378738A1

公开(公告)日：2021-12-09

申请号：US17288408

申请日：2019-10-23

申请人： CREO MEDICAL LIMITED

发明人： Christopher Paul HANCOCK ,  William TAPLIN ,  George ULLRICH ,  Shaun PRESTON ,  David WEBB ,  Sandra SWAIN ,  Malcolm WHITE

IPC分类号： A61B18/18 ,  A61B18/14

摘要： An electrosurgical device having a radiating tip portion for delivering electromagnetic energy to biological tissue, where the electrosurgical device is disposed in a catheter. The electrosurgical device is movable relative to the catheter between a deployed position where the radiating tip portion is exposed and a retracted position where the radiating tip portion is contained within the catheter. In this manner, the radiating tip portion may be retracted until the moment when it is to be used. This may facilitate insertion of the device through an instrument channel of a surgical scoping device. In particular, this may prevent the radiating tip portion from catching on the instrument channel when the device is inserted into the instrument channel, which could cause damage to the instrument channel and/or radiating tip portion.

公开(公告)号：US20230128952A1

公开(公告)日：2023-04-27

申请号：US18068147

申请日：2022-12-19

申请人： CREO MEDICAL LIMITED

发明人： Simon MEADOWCROFT ,  Christopher Paul HANCOCK ,  George ULLRICH ,  David WEBB ,  Louis TURNER ,  Juline Mark EBBUTT

IPC分类号： A61B18/18 ,  A61B18/14

摘要： An electrosurgical apparatus and method for performing thermal treatment in the gastrointestinal tract, e.g. to ablate duodenal mucosal tissue. The apparatus comprises an instrument having a flexible cable and an applicator suitable for use with a gastroscope, which can be deployed within a patient to delivery energy in a targeted or otherwise controllable manner. The applicator can deliver microwave energy by radiation. The direct and depth-limited nature of microwave energy can be make it more effective than treatments that rely on thermal conduction. The applicator may include a radially extendable portion arranged to move an microwave energy delivery structure into contact with duodenal mucosal tissue at the treatment region. The applicator may comprise any of a balloon, bipolar radiator, movable paddle, and rotatable roller element.