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公开(公告)号：US11174271B2
公开(公告)日：2021-11-16
申请号：US16462153
申请日：2017-11-21
发明人： Mark Spyvee , Michael Lewis
IPC分类号： C07D498/04 , A61P35/00 , C07D211/88 , C07D213/69 , C07D213/79 , C07D237/16 , C07D239/14 , C07D239/22 , C07D239/54 , C07D241/18 , C07D251/20 , C07D251/30 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D413/06 , C07D471/04 , C07D233/72
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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公开(公告)号：US10858344B2
公开(公告)日：2020-12-08
申请号：US16462168
申请日：2017-11-21
发明人： Mark Spyvee
IPC分类号： C07D403/14 , C07D207/404 , A61P35/00 , C07D221/00 , C07D233/02 , C07D239/22 , C07D241/08 , C07D251/30 , C07D401/06 , C07D403/12 , C07D405/12 , C07D405/14 , C07D413/12 , C07D413/14
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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公开(公告)号：US20190276410A1
公开(公告)日：2019-09-12
申请号：US16462173
申请日：2017-11-21
发明人： Mark Spyvee , Robert D. Ladner
IPC分类号： C07D233/74 , A61P35/00 , C07D209/48 , C07D403/06 , C07D401/12
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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公开(公告)号：US20180334431A1
公开(公告)日：2018-11-22
申请号：US15740783
申请日：2016-07-07
发明人： Robert D. Ladner , Mark Spyvee , Pravin S. Shirude
IPC分类号： C07D207/40 , C12Q1/6886 , A61P35/00 , C07D239/22 , C07D211/88 , C07D277/34
CPC分类号： C07D207/40 , A61P35/00 , C07D211/88 , C07D239/22 , C07D241/08 , C07D251/20 , C07D277/34 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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公开(公告)号：US11124485B2
公开(公告)日：2021-09-21
申请号：US16773411
申请日：2020-01-27
发明人： Mark Spyvee , Pravin S. Shirude
IPC分类号： A61K31/513 , C07D239/22 , C07D211/88 , C07D207/404 , A61P35/00
摘要： Provided herein are dUTPase inhibitors of Formula (I), compositions comprising such compounds and methods of using such compounds and compositions
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公开(公告)号：US20200255385A1
公开(公告)日：2020-08-13
申请号：US16789687
申请日：2020-05-04
发明人： Mark Spyvee , Pravin S. Shirude
IPC分类号： C07D233/74 , C07D277/34 , C07D263/44 , C07D251/10 , C07D249/12 , C07D241/08 , C07D239/22 , C07D233/46 , C07D207/404 , C07D207/36 , C07D487/04 , C07D405/12 , C07D403/12 , C07D401/12 , A61P35/00 , C07D207/40 , C07D211/88 , A61K31/4015 , C07F9/6506
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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公开(公告)号：US10570098B2
公开(公告)日：2020-02-25
申请号：US15741202
申请日：2016-07-07
发明人： Mark Spyvee , Pravin S. Shirude
IPC分类号： A61K31/4015 , C07D233/74 , C07F9/6506 , C07D211/88 , C07D207/40 , A61P35/00 , C07D401/12 , C07D403/12 , C07D405/12 , C07D487/04 , C07D207/36 , C07D207/404 , C07D233/46 , C07D239/22 , C07D241/08 , C07D249/12 , C07D251/10 , C07D263/44 , C07D277/34
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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公开(公告)号：US10544105B2
公开(公告)日：2020-01-28
申请号：US15741205
申请日：2016-07-07
发明人： Mark Spyvee , Pravin S. Shirude
IPC分类号： C07D239/22 , C07D211/88 , C07D207/404 , A61K31/513 , A61P35/00
摘要： Provided herein are dUTPase inhibitors of Formula (I), compositions comprising such compounds and methods of using such compounds and compositions
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公开(公告)号：US20220402879A1
公开(公告)日：2022-12-22
申请号：US17320650
申请日：2021-05-14
发明人： Mark Spyvee , Pravin S. Shirude
IPC分类号： C07D233/74 , C07D401/12 , C07F9/6506 , C07D241/08 , C07D263/44 , C07D405/12 , C07D487/04 , C07D207/404 , C07D211/88 , A61P35/00 , C07D207/36 , C07D207/40 , C07D249/12 , A61K31/4015 , C07D403/12 , C07D233/46 , C07D251/10 , C07D277/34 , C07D239/22
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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公开(公告)号：US11518746B2
公开(公告)日：2022-12-06
申请号：US17092123
申请日：2020-11-06
发明人： Mark Spyvee , Robert D. Ladner
IPC分类号： C07D209/48 , C07D233/72 , C07D233/74 , A61P35/00 , C07D401/12 , C07D403/06 , A61K31/4015 , A61K31/4166
摘要： Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.
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