公开(公告)号：US12066430B2

公开(公告)日：2024-08-20

申请号：US16633451

申请日：2018-07-24

Applicant: California Institute of Technology

Inventor： Michael T. Bethune ,  Jocelyn T. Kim ,  David Baltimore ,  Guideng Li ,  Stephanie Wong

IPC: G01N33/50 ,  G01N33/566 ,  G06F16/27

CPC classification number: G01N33/505 ,  G01N33/566 ,  G06F16/27

Abstract: Disclosed herein are trogocytosis based TCR ligand discovery platforms and methods of using the same, trogocytosis based TCR discovery platforms and methods of using the same, and trogocytosis based ligand discovery platforms and methods of using the same. Also disclosed herein are isolated cells, nucleotides, sequences, and sequence databases produced using trogocytosis based discovery platforms.

公开(公告)号：US20200309765A1

公开(公告)日：2020-10-01

申请号：US16633451

申请日：2018-07-24

Applicant: Michael T. BETHUNE ,  David BALTIMORE ,  California Institute of Technology ,  PACT PHARMA, INC.

Inventor： Michael T. Bethune ,  Jocelyn T. Kim ,  David Baltimore ,  Guideng Li ,  Stephanie Wong

IPC: G01N33/50 ,  G01N33/566 ,  G06F16/27

Abstract: Disclosed herein are trogocytosis based TCR ligand discovery platforms and methods of using the same, trogocytosis based TCR discovery platforms and methods of using the same, and trogocytosis based ligand discovery platforms and methods of using the same. Also disclosed herein are isolated cells, nucleotides, sequences, and sequence databases produced using trogocytosis based discovery platforms.