公开(公告)号：US10336678B2

公开(公告)日：2019-07-02

申请号：US15977638

申请日：2018-05-11

Applicant: California Institute of Technology

Inventor： Samantha E. Shockley ,  John C. Hethcox ,  Brian M. Stoltz

IPC: C07C51/08 ,  C07C57/03 ,  C07C67/22 ,  C07C69/52 ,  C07C233/09 ,  B01J31/12 ,  B01J31/18 ,  C07C231/18 ,  C07C201/12 ,  C07C253/30 ,  C07C67/00

Abstract: The present disclosure provides methods for enantioselective synthesis of acyclic α-quaternary carboxylic acid derivatives via iridium-catalyzed allylic alkylation.