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公开(公告)号:US20210052632A1
公开(公告)日:2021-02-25
申请号:US16959519
申请日:2019-01-16
Applicant: Cambridge Enterprise Limited
Inventor: Melinda DUER , David REID , Uliana BASHTANOVA
IPC: A61K31/7135 , A61K31/28
Abstract: The disclosure provides a selective inhibitor of DNA-binding to poly (ADP-ribose) polymerase 1 (PARP1), or a pharmaceutically acceptable salt or solvate thereof, for use in treating, ameliorating or preventing cancer. The treatment may be given to a subject suffering from or at risk of osteoporosis or a subject requiring a long-term therapy.