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1.发明授权公开(公告)号：US09221872B2
公开(公告)日：2015-12-29
申请号：US14313264
申请日：2014-06-24
申请人： CanBas Co., Ltd.
发明人： Takumi Kawabe , Naoki Mine , Naoya Saito , Keiichi Sakakibara , Takuji Sato
摘要： This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells. While the invention is not limited to any particular mechanism, the compounds of the invention appear to function at least in part by inhibiting G2 cell cycle checkpoint. Thus, invention compounds can be used to inhibit cell growth alone or be used in combination with a nucleic acid damaging treatment to inhibit cell growth.
摘要翻译： 本发明提供了可用于治疗细胞增殖性疾病（例如与良性和恶性肿瘤细胞相关的那些）的肽和肽模拟物的化合物。 虽然本发明不限于任何特定的机制，但是本发明的化合物至少部分通过抑制G2细胞周期检查点起作用。 因此，本发明化合物可用于单独抑制细胞生长或与核酸损伤处理组合使用以抑制细胞生长。
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2.发明申请PEPTIDES AND PEPTIDOMIMETICS IN COMBINATION USES AND TREATMENTS FOR CANCER PATIENT SUBPOPULATIONS 有权组合使用和治疗癌症患者子宫颈癌的方法和细胞因子公开(公告)号：US20150056301A1
公开(公告)日：2015-02-26
申请号：US14313264
申请日：2014-06-24
申请人： CanBas Co., Ltd.
发明人： Takumi Kawabe , Naoki Mine , Naoya Saito , Keiichi Sakakibara , Takuji Sato
摘要： This invention provides compounds including peptides and peptidomimetics that can be used to treat cell proliferative disorders, such as those associated with benign and malignant tumor cells. While the invention is not limited to any particular mechanism, the compounds of the invention appear to function at least in part by inhibiting G2 cell cycle checkpoint. Thus, invention compounds can be used to inhibit cell growth alone or be used in combination with a nucleic acid damaging treatment to inhibit cell growth.
摘要翻译： 本发明提供了可用于治疗细胞增殖性疾病（例如与良性和恶性肿瘤细胞相关的那些）的肽和肽模拟物的化合物。 虽然本发明不限于任何特定的机制，但是本发明的化合物至少部分通过抑制G2细胞周期检查点起作用。 因此，本发明化合物可用于单独抑制细胞生长或与核酸损伤处理组合使用以抑制细胞生长。
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