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公开(公告)号：US20220259275A1
公开(公告)日：2022-08-18
申请号：US17595960
申请日：2020-05-28
Applicant: Case Western Reserve University
Inventor： Parameswaran Ramakrishnan , Jonathan K. Pokorski
Abstract: The present disclosure relates to peptoids for inhibiting O-GlcNAcylated proteins, and in particular, the c-Rel peptide of NF-kappaB. The compounds can be used in the prevention or treatment of diseases of conditions having elevated levels of O-GlcNAcylation, such as autoimmune diseases, conditions that are related to hyperglycemia, or cancers.
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