HEREDITARY CATARACT STATUS IN CANINES BASED ON HSF4 GENE MARKER
    1.
    发明申请
    HEREDITARY CATARACT STATUS IN CANINES BASED ON HSF4 GENE MARKER 有权
    基于HSF4基因标记的CANEDITAR CATARACT状态

    公开(公告)号:US20100168211A1

    公开(公告)日:2010-07-01

    申请号:US12294655

    申请日:2007-03-29

    IPC分类号: A61K31/7088 C12Q1/68

    摘要: The invention provides methods for assessing the Hereditary cataract (HC) status of a canine mammal, which methods comprise use of an HSF4 marker to assess the status. Preferred canine mammals are dogs selected from the following breeds: Staffordshire bull terrier, Boston terrier, French bulldog, Mastiff, Bulldog, Boxer, Bullmastiff, Miniature bull terrier.

    摘要翻译: 本发明提供了用于评估犬哺乳动物的遗传性白内障(HC)状态的方法,该方法包括使用HSF4标记来评估状态。 优选的犬哺乳动物是选自以下品种的狗:斯塔福郡郡斗牛犬,波士顿梗犬,法国斗牛犬,獒犬,牛头犬,拳击手,獒犬,小型斗牛犬。

    Hereditary cataract status in canines based on HSF4 gene marker
    2.
    发明授权
    Hereditary cataract status in canines based on HSF4 gene marker 有权
    基于HSF4基因标记的犬科遗传性白内障状态

    公开(公告)号:US08124337B2

    公开(公告)日:2012-02-28

    申请号:US12294655

    申请日:2007-03-29

    IPC分类号: C07H21/04 C12Q1/68

    摘要: The invention provides methods for assessing the Hereditary cataract (HC) status of a canine mammal, which methods comprise use of an HSF4 marker to assess the status. Preferred canine mammals are dogs selected from the following breeds: Staffordshire bull terrier, Boston terrier, French bulldog, Mastiff, Bulldog, Boxer, Bullmastiff, Miniature bull terrier.

    摘要翻译: 本发明提供了用于评估犬哺乳动物的遗传性白内障(HC)状态的方法,该方法包括使用HSF4标记来评估状态。 优选的犬哺乳动物是选自以下品种的狗:斯塔福郡郡斗牛犬,波士顿梗犬,法国斗牛犬,獒犬,牛头犬,拳击手,獒犬,小型斗牛犬。

    TTC8 AS PROGNOSTIC GENE FOR PROGRESSIVE RETINAL ATROPHY IN DOGS
    3.
    发明申请
    TTC8 AS PROGNOSTIC GENE FOR PROGRESSIVE RETINAL ATROPHY IN DOGS 有权
    TTC8作为预防性进展性胃肠病的原发性基因

    公开(公告)号:US20150148406A1

    公开(公告)日:2015-05-28

    申请号:US14404291

    申请日:2013-05-24

    IPC分类号: C12Q1/68

    摘要: The invention relates to the use of the TTC8 gene as a biomarker for the prognosis of a canine mammal developing progressive retinal atrophy. The invention also relates to in vitro methods of prognosing progressive retinal atrophy in a canine mammal by detecting a genetic variation within the TTC8 gene and to primers and prognostic kits for use in said method.

    摘要翻译: 本发明涉及TTC8基因作为发展进行性视网膜萎缩的犬哺乳动物预后的生物标志物的用途。 本发明还涉及通过检测TTC8基因内的遗传变异以及用于所述方法的引物和预后试剂盒来预测犬哺乳动物中进行性视网膜萎缩的体外方法。