公开(公告)号：US20200377606A1

公开(公告)日：2020-12-03

申请号：US16094737

申请日：2017-04-18

申请人： Celldex Therapeutics, Inc.

发明人： Tibor KELER ,  Joel GOLDSTEIN ,  Laura A. VITALE ,  Lizhen HE ,  Tom O'NEILL ,  Andrea CROCKER ,  Karuna SUNDARAPANDIYAN ,  Lawrence J. THOMAS ,  Jenifer WIDGER

IPC分类号： C07K16/28 ,  A61K39/395 ,  A61K39/385

摘要： Isolated monoclonal agonistic antibodies which bind to human CD40 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

公开(公告)号：US20190322743A1

公开(公告)日：2019-10-24

申请号：US16376585

申请日：2019-04-05

申请人： Celldex Therapeutics, Inc.

发明人： Tibor KELER ,  Joel GOLDSTEIN ,  Laura A. VITALE ,  Lizhen HE ,  Tom O'NEILL ,  Andrea CROCKER ,  Karuna SUNDARAPANDIYAN ,  Lawrence J. THOMAS ,  Jenifer WIDGER

IPC分类号： C07K16/28 ,  C07K14/715 ,  C07K14/54 ,  A61K39/395

摘要： Isolated monoclonal agonistic antibodies which bind to human CD40 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

公开(公告)号：US20200369768A1

公开(公告)日：2020-11-26

申请号：US16986613

申请日：2020-08-06

申请人： Celldex Therapeutics, Inc.

发明人： Tibor KELER ,  Joel GOLDSTEIN ,  Laura A. VITALE ,  Lizhen HE ,  Tom O'NEILL ,  Andrea CROCKER ,  Karuna SUNDARAPANDIYAN ,  Lawrence J. THOMAS ,  Jenifer WIDGER

IPC分类号： C07K16/28 ,  A61K39/395 ,  C07K14/54 ,  C07K14/715

摘要： Isolated monoclonal agonistic antibodies which bind to human CD40 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

公开(公告)号：US20210147538A1

公开(公告)日：2021-05-20

申请号：US17145052

申请日：2021-01-08

申请人： Celldex Therapeutics, Inc.

发明人： Tibor KELER ,  Joel GOLDSTEIN ,  Laura A. VITALE ,  Lizhen HE ,  Tom O'NEILL ,  Andrea CROCKER ,  Karuna SUNDARAPANDIYAN ,  Lawrence J. THOMAS ,  Jenifer WIDGER

IPC分类号： C07K16/28 ,  A61K39/395 ,  A61K39/385 ,  C07K14/54 ,  C07K14/715

摘要： Isolated monoclonal agonistic antibodies which bind to human CD40 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.

公开(公告)号：US20180066053A1

公开(公告)日：2018-03-08

申请号：US15490589

申请日：2017-04-18

申请人： Celldex Therapeutics, Inc.

发明人： Tibor KELER ,  Joel GOLDSTEIN ,  Laura A. VITALE ,  Lizhen HE ,  Tom O'NEILL ,  Andrea CROCKER ,  Karuna SUNDARAPANDIYAN ,  Lawrence J. THOMAS ,  Jenifer Widger

IPC分类号： C07K16/28 ,  C07K14/715 ,  C07K14/54

CPC分类号： C07K16/2803 ,  A61K39/39541 ,  A61K2039/505 ,  C07K14/54 ,  C07K14/70575 ,  C07K14/715 ,  C07K16/2878 ,  C07K2317/34 ,  C07K2317/73 ,  C07K2317/74 ,  C07K2317/75 ,  C07K2317/92 ,  A61K2300/00

摘要： Isolated monoclonal agonistic antibodies which bind to human CD40 and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for using the antibodies.