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公开(公告)号：US20160095901A1
公开(公告)日：2016-04-07
申请号：US14884115
申请日：2015-10-15
IPC分类号： A61K38/17
CPC分类号： A61K38/1709 , A61K38/17 , A61K38/18 , A61K45/00 , A61K47/50 , C07K1/04 , C07K1/042 , C07K14/775 , Y10T428/2982
摘要： The present disclosure relates to lipoprotein complexes and lipoprotein populations and their use in the treatment and/or prevention of dyslipidemic diseases, disorders, and/or conditions. The disclosure further relates to recombinant expression of apolipoproteins, purification of apolipoproteins, and production of lipoprotein complexes using thermal cycling-based methods.
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公开(公告)号：US20140206600A1
公开(公告)日：2014-07-24
申请号：US14085685
申请日：2013-11-20
发明人： Jean-Louis DASSEUX
IPC分类号： C07K14/775 , A61K31/688 , A61K31/685 , A61K38/17
CPC分类号： A61K38/1709 , A61K9/0095 , A61K9/127 , A61K9/1275 , A61K31/685 , A61K31/688 , A61K38/00 , A61K49/0008 , C07K14/775
摘要： The present disclosure provides charged lipoprotein complexes that include as one component a negatively charged phospholipid that is expected to impart the complexes with improved therapeutic properties.
摘要翻译： 本公开提供了带电荷的脂蛋白复合物，其包括作为一种组分的带负电荷的磷脂，其预期赋予复合物改善的治疗性质。
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公开(公告)号：US20150152164A1
公开(公告)日：2015-06-04
申请号：US14334519
申请日：2014-07-17
IPC分类号： C07K14/775 , A61K38/17 , A61K47/48
CPC分类号： A61K38/1709 , A61K38/17 , A61K38/18 , A61K45/00 , A61K47/50 , C07K1/04 , C07K1/042 , C07K14/775 , Y10T428/2982
摘要： The present disclosure relates to lipoprotein complexes and lipoprotein populations and their use in the treatment and/or prevention of dyslipidemic diseases, disorders, and/or conditions. The disclosure further relates to recombinant expression of apolipoproteins, purification of apolipoproteins, and production of lipoprotein complexes using thermal cycling-based methods.
摘要翻译： 本公开涉及脂蛋白复合物和脂蛋白种群及其在治疗和/或预防血脂异常疾病，病症和/或病症中的用途。 本公开还涉及载脂蛋白的重组表达，载脂蛋白的纯化，以及使用基于热循环的方法产生脂蛋白复合物。
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公开(公告)号：US20190298800A1
公开(公告)日：2019-10-03
申请号：US16397944
申请日：2019-04-29
摘要： The present disclosure relates to lipoprotein complexes and lipoprotein populations and their use in the treatment and/or prevention of dyslipidemic diseases, disorders, and/or conditions. The disclosure further relates to recombinant expression of apolipoproteins, purification of apolipoproteins, and production of lipoprotein complexes using thermal cycling-based methods.
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公开(公告)号：US20170182121A1
公开(公告)日：2017-06-29
申请号：US15398219
申请日：2017-01-04
发明人： Jean-Louis DASSEUX
IPC分类号： A61K38/17 , A61K31/688 , A61K31/685 , A61K9/00 , A61K9/127
CPC分类号： A61K38/1709 , A61K9/0095 , A61K9/127 , A61K9/1275 , A61K31/685 , A61K31/688 , A61K38/00 , A61K49/0008 , C07K14/775
摘要： The present disclosure provides charged lipoprotein complexes that include as one component a negatively charged phospholipid that is expected to impart the complexes with improved therapeutic properties.
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公开(公告)号：US20140213501A1
公开(公告)日：2014-07-31
申请号：US14103686
申请日：2013-12-11
IPC分类号： A61K47/48
CPC分类号： A61K38/1709 , A61K38/17 , A61K38/18 , A61K45/00 , A61K47/50 , C07K1/04 , C07K1/042 , C07K14/775 , Y10T428/2982
摘要： The present disclosure relates to lipoprotein complexes and lipoprotein populations and their use in the treatment and/or prevention of dyslipidemic diseases, disorders, and/or conditions. The disclosure further relates to recombinant expression of apolipoproteins, purification of apolipoproteins, and production of lipoprotein complexes using thermal cycling-based methods.
摘要翻译： 本公开涉及脂蛋白复合物和脂蛋白种群及其在治疗和/或预防血脂异常疾病，病症和/或病症中的用途。 本公开还涉及载脂蛋白的重组表达，载脂蛋白的纯化，以及使用基于热循环的方法产生脂蛋白复合物。
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