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公开(公告)号:US20100120902A1
公开(公告)日:2010-05-13
申请号:US12532815
申请日:2008-03-24
申请人: Chandra Kant Katiyar , Anil Kanaujia , Rajeev Duggar , Satyapal Singh Yadav , Navin Sharma , Abhijit Ray , Rajkumar Shirumalla , Malini Bajpai , Gyanesh Shukla , Baddireddi Subhadra Lakshmi , Kontham Sanathkumar Vinaykumar
发明人: Chandra Kant Katiyar , Anil Kanaujia , Rajeev Duggar , Satyapal Singh Yadav , Navin Sharma , Abhijit Ray , Rajkumar Shirumalla , Malini Bajpai , Gyanesh Shukla , Baddireddi Subhadra Lakshmi , Kontham Sanathkumar Vinaykumar
IPC分类号: A61K31/352 , A61P29/00 , A61P19/02 , A61P19/00
CPC分类号: A61K36/185
摘要: The present invention relates to standardized extracts of Boerhaavia diffusa, wherein the extracts have anti inflammatory and analgesic activities. The present invention also includes bioassay guided fractionation of Boerhaavia diffusa leading to the identification of bioactive markers; processes for the isolation of the bioactive markers; processes for the preparation of the extracts enriched with bioactive markers from Boerhaavia diffusa; pharmaceutical compositions comprising bioactive markers, or standardized extracts of Boerhaavia diffusa and methods of standardization of the extracts.
摘要翻译: 本发明涉及双歧杆菌的标准化提取物,其中提取物具有抗炎和止痛活性。 本发明还包括生物测定引导分离的Boerhaavia diffusa,导致鉴定生物活性标记; 分离生物活性标记物的方法; 用于制备富含Boerhaavia diffusa的生物活性标记物的提取物的方法; 包含生物活性标记物或Boerhaavia diffusa的标准化提取物的药物组合物和提取物的标准化方法。
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公开(公告)号:US20090018174A1
公开(公告)日:2009-01-15
申请号:US12093041
申请日:2006-11-08
IPC分类号: A61K31/365 , A61K31/424
CPC分类号: A61K31/7048
摘要: Provided herein are macrolide derivatives that can be useful in treating or preventing inflammatory diseases. Also provided are pharmaceutical compositions comprising one or more macrolide derivatives optionally together with one or more pharmaceutically acceptable carriers, excipients, diluents or mixtures thereof, as well as methods for treating or preventing inflammatory diseases.
摘要翻译: 本文提供可用于治疗或预防炎性疾病的大环内酯衍生物。 还提供药物组合物,其包含一种或多种大环内酯衍生物,任选与一种或多种药学上可接受的载体,赋形剂,稀释剂或其混合物,以及治疗或预防炎性疾病的方法。
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公开(公告)号:US20090221600A1
公开(公告)日:2009-09-03
申请号:US12088538
申请日:2006-09-28
申请人: Ashwani Kumar Verma , Yogesh Bhaskarrao Waman , Venkata P. Palle , Atul Kondaskar , Abhijit Ray , Malini Bajpai , Geeta Sharma
发明人: Ashwani Kumar Verma , Yogesh Bhaskarrao Waman , Venkata P. Palle , Atul Kondaskar , Abhijit Ray , Malini Bajpai , Geeta Sharma
IPC分类号: A61K31/519 , C07D471/04 , A61P29/00
CPC分类号: C07D471/04
摘要: Provided are novel pyrido-pyrimidine derivatives, having the structure of Formula (I): which can be used as anti-inflammatory agents. Also provided are pharmaceutical compositions comprising one or more pyrido-pyrimidine derivatives, as well as methods of treating autoimmune diseases, inflammation or associated pathologies, including for example, sepsis, rheumatoid arthritis, inflammatory bowel disease, type-1 diabetes, asthma, chronic obstructive pulmonary disorder, organ transplant rejection and psoriasis, comprising administering such compounds or pharmaceutical compositions comprising them.
摘要翻译: 提供具有式(I)结构的新型吡啶并嘧啶衍生物:其可用作抗炎剂。 还提供了包含一种或多种吡啶并嘧啶衍生物的药物组合物,以及治疗自身免疫性疾病,炎症或相关病理学的方法,包括例如败血症,类风湿性关节炎,炎性肠病,1型糖尿病,哮喘,慢性阻塞性 肺部疾病,器官移植排斥和牛皮癣,包括施用这样的化合物或包含它们的药物组合物。
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