公开(公告)号：US20120271558A1

公开(公告)日：2012-10-25

申请号：US13515006

申请日：2010-01-19

申请人： Cheol Goo Hur ,  Jung Eun Kim ,  Bong Woo Lee ,  Seung Won Lee ,  Ji Man Hong

发明人： Cheol Goo Hur ,  Jung Eun Kim ,  Bong Woo Lee ,  Seung Won Lee ,  Ji Man Hong

IPC分类号： G06F19/24

CPC分类号： G16B40/00

摘要： The present invention relates to a system and a method for quickly and accurately identifying and classifying resistance genes of a plant from a protein or DNA sequence. In order to identify and classify resistance genes of a plant using a hidden marcov model, conceived is a profile matrix made using a protein sequence of a domain which is encoded by the resistance genes, and a system for identifying the domain of the resistance genes using the profile matrix and classifying the resistance genes by domain combination. The present invention enables effective identification and classification of the resistance genes of a plant using the profile matrix and program, of which the nucleotide base sequence or protein sequence is detected.

摘要翻译： 本发明涉及从蛋白质或DNA序列快速准确地鉴定和分类植物的抗性基因的系统和方法。 为了使用隐藏的marcov模型来鉴定和分类植物的抗性基因，构想是使用由抗性基因编码的结构域的蛋白质序列制成的轮廓矩阵，以及用于鉴定抗性基因的结构域的系统，其使用 轮廓矩阵，并通过域组合对抗性基因进行分类。 本发明可以使用检测到核苷酸碱基序列或蛋白质序列的轮廓矩阵和程序有效地鉴定和分类植物的抗性基因。

公开(公告)号：US09956265B2

公开(公告)日：2018-05-01

申请号：US14113762

申请日：2012-04-26

申请人： Ji Man Hong

发明人： Ji Man Hong

IPC分类号： A61K38/18 ,  A61M1/00

CPC分类号： A61K38/1816 ,  A61M1/00

摘要： The present invention relates to a composition comprising erythropoietin (EPO) as an active ingredient for aiding surgical procedures for treating ischemic vascular diseases. The present invention also relates to a method for treating ischemic vascular diseases using a combination of the composition and the invasive procedure for sufficient disruption of the physical barriers for new neovascularization. The composition for aiding surgical or invasive procedures according to the present invention would be beneficial for the success rate and safety issue of a variety of surgical procedures such as minimally invasive operations performed on a patient suffering from a variety of cerebral ischemic vascular diseases including ischemic stroke and moyamoya disease, and can be widely used in the treatment of a variety of ischemic vasculopathies in cardiac or peripheral artery system.

公开(公告)号：US20140045748A1

公开(公告)日：2014-02-13

申请号：US14113762

申请日：2012-04-26

申请人： Ji Man Hong

发明人： Ji Man Hong

IPC分类号： A61K38/18

CPC分类号： A61K38/1816 ,  A61M1/00

摘要： The present invention relates to a composition comprising erythropoietin (EPO) as an active ingredient for aiding surgical procedures for treating ischemic vascular diseases. The present invention also relates to a method for treating ischemic vascular diseases using said composition. The composition for aiding surgical procedures according to the present invention may improve the success rate of a variety of surgical procedures including multiple cutting operations performed on an adult patient suffering from a variety of ischemic vascular diseases including moyamoya disease, and can be widely used in the treatment of a variety of ischemic vascular diseases.

摘要翻译： 本发明涉及一种包含促红细胞生成素（EPO）作为有助于治疗缺血性血管疾病的外科手术的活性成分的组合物。 本发明还涉及使用所述组合物治疗缺血性血管疾病的方法。 根据本发明的用于辅助外科手术的组合物可以提高各种外科手术的成功率，包括对患有多种缺血性血管疾病（包括moyamoya病）的成年患者进行的多次切割操作，并可广泛用于 治疗各种缺血性血管疾病。