ELECTROSPINNING MANUFACTURE FOR DRUG CARRIERS
    2.
    发明申请
    ELECTROSPINNING MANUFACTURE FOR DRUG CARRIERS 有权
    电动汽车制造商

    公开(公告)号:US20120013046A1

    公开(公告)日:2012-01-19

    申请号:US12836318

    申请日:2010-07-14

    IPC分类号: B29C47/00

    摘要: An electrospinning manufacture for drug carriers is disclosed. The method comprises a preliminary step mixing a predetermined drug, an alginate, and a saline to obtain a mixture; an electric field establishing step providing a collection plate and an emitter filled with divalent cation agent and the mixture individually, wherein an electric field is applied to the collection plate and the emitter to form a voltage therebetween; and an electrospinning step sequentially dropping the mixture from the emitter into the divalent cation agent filled in the collection plate via the driving of the electric field, triggering a crosslinking-gelating reaction between the divalent cation and the alginate, wherein a plurality of gel particles is produced for a coating of the predetermined drug presenting a drug carrier performance.

    摘要翻译: 公开了用于药物载体的静电纺丝制造。 该方法包括将预定药物,藻酸盐和盐水混合以获得混合物的预备步骤; 电场建立步骤,提供收集板和填充有二价阳离子剂的发射体和所述混合物,其中电场施加到收集板和发射极以在它们之间形成电压; 以及静电纺丝步骤,通过驱动电场,将混合物从发射体顺序滴落到填充在收集板中的二价阳离子剂中,引发二价阳离子和藻酸盐之间的交联凝胶化反应,其中多个凝胶颗粒为 产生用于呈现药物载体性能的预定药物的涂层。

    DRUG CARRIER FOR TREATING OF GASTROINTESTINAL ULCER
    3.
    发明申请
    DRUG CARRIER FOR TREATING OF GASTROINTESTINAL ULCER 审中-公开
    用于治疗胃肠道溃疡的药物载体

    公开(公告)号:US20120009264A1

    公开(公告)日:2012-01-12

    申请号:US12832673

    申请日:2010-07-08

    IPC分类号: A61K9/14 A61P1/04 A61K31/4439

    CPC分类号: A61K31/4439 A61K9/5036

    摘要: A drug carrier for treating of gastrointestinal ulcer comprises a microspheroid having a substrate and a plurality of particles distributed over and covered by the substrate, wherein the substrate is alginate and the plurality of particles is a drug for treating of gastrointestinal ulcer; and a coat covering up the surface of the microspheroid, which contains chitosan.

    摘要翻译: 用于治疗胃肠溃疡的药物载体包括具有底物和分布在基底上并被基底覆盖的多个颗粒的微球,其中所述底物是藻酸盐,并且所述多个颗粒是治疗胃肠溃疡的药物; 和覆盖包含壳聚糖的微球表面的外套。