公开(公告)号：US20230321795A1

公开(公告)日：2023-10-12

申请号：US17716081

申请日：2022-04-08

Applicant: Yung-Sheng Lin ,  Shih-Liang Huang

Inventor： Yung-Sheng Lin ,  Shih-Liang Huang

IPC: B25B13/50

CPC classification number: B25B13/505

Abstract: A pipe plier structure includes a first body, a second body, a pivot member, and a locking member. The first body is provided with multiple first teeth, an arc line, an axis, a first vertical line, a radius, a first angle, and a second angle. The second body is provided with multiple second teeth, multiple third teeth, a second vertical line, a first connecting line, a second connecting line, a third angle, a fourth angle, a concave face, a fifth angle, a sixth angle, a seventh angle, and an eighth angle. The pivot member is assembled with the first body and the second body. The locking member is assembled with the first body and the second body. The locking member provides an elastically restoring force to the first body and the second body after the second body is extended outward relative to the first body.

公开(公告)号：US08540504B2

公开(公告)日：2013-09-24

申请号：US12723945

申请日：2010-03-15

Applicant: Kuen-Wey Shieh ,  Chien-Chung Chen ,  Yung-Sheng Lin

Inventor： Kuen-Wey Shieh ,  Chien-Chung Chen ,  Yung-Sheng Lin

IPC: B29C47/00

CPC classification number: D01D5/0092

Abstract: An electrospinning equipment is provided. The electrospinning equipment includes a power supply, a collector and a material supply electrically connected to the power supply facing the collector and having a spinneret and a guide unit coupled to the spinneret and bent toward the collector, and the spinneret is configured at a central portion of the guide unit.

Abstract translation: 提供静电纺丝设备。 静电纺丝设备包括电源，集电器和材料供应源，电源连接到面向收集器的电源，并具有连接到喷丝头并且朝向收集器弯曲的喷丝头和引导单元，并且喷丝头被配置在中心部分 的导向单元。

公开(公告)号：US20110256231A1

公开(公告)日：2011-10-20

申请号：US12763408

申请日：2010-04-20

Applicant: Yung-Sheng Lin ,  Chun-Ting Lin ,  Keng-Shiang Huang ,  Chih-Hui Yang ,  Sheng-Yi Hsiao ,  Chih-Cheng Huang ,  Shih-Feng Tseng

Inventor： Yung-Sheng Lin ,  Chun-Ting Lin ,  Keng-Shiang Huang ,  Chih-Hui Yang ,  Sheng-Yi Hsiao ,  Chih-Cheng Huang ,  Shih-Feng Tseng

IPC: A61K9/14

CPC classification number: A61K9/1647 ,  A61K9/1652 ,  A61K9/1694

Abstract: A method for preparing drug in hemisphere-shaped dosage form. A high molecular weight solution containing the drug is prepared, and the solution is then dropped on a base material. The interface phenomena between the solution and different base materials makes the drop of high molecular weight solution containing the drug form a hemisphere-shape. After solidifying by cross-link or evaporation, the drug in hemisphere-shaped dosage form is obtained. The advantages of the preparation method are a simple and fast process, and simple operation. Applications of the method to prepare a drug in hemisphere-shaped dosage form are also provided.

Abstract translation: 制备半球形剂型的药物的方法。 制备含有药物的高分子量溶液，然后将溶液滴在基材上。 溶液与不同基材之间的界面现象使得含有药物的高分子量溶液的下降形成半球形。 通过交联或蒸发固化后，得到半球形剂型。 制备方法的优点是简单快速的过程，操作简单。 还提供了制备半球形剂型药物的方法的应用。

公开(公告)号：US20100173035A1

公开(公告)日：2010-07-08

申请号：US12723945

申请日：2010-03-15

Applicant: Kuen-Wey Shieh ,  Chien-Chung Chen ,  Yung-Sheng Lin

Inventor： Kuen-Wey Shieh ,  Chien-Chung Chen ,  Yung-Sheng Lin

IPC: B29B13/08

CPC classification number: D01D5/0092

Abstract: An electrospinning equipment is provided. The electrospinning equipment includes a power supply, a collector and a material supply electrically connected to the power supply facing the collector and having a spinneret and a guide unit coupled to the spinneret and bent toward the collector, and the spinneret is configured at a central portion of the guide unit.

Abstract translation: 提供静电纺丝设备。 静电纺丝设备包括电源，集电器和材料供应源，电源连接到面向收集器的电源，并具有连接到喷丝头并且朝向收集器弯曲的喷丝头和引导单元，并且喷丝头被配置在中心部分 的导向单元。

公开(公告)号：US20090053287A1

公开(公告)日：2009-02-26

申请号：US11926575

申请日：2007-10-29

Applicant: Ching-Cheng HUANG ,  Quang-Wei CHANG ,  Yung-Sheng LIN ,  Ting-Kai LEUNG

Inventor： Ching-Cheng HUANG ,  Quang-Wei CHANG ,  Yung-Sheng LIN ,  Ting-Kai LEUNG

IPC: A61L15/00

CPC classification number: A61L15/44 ,  A61L15/20 ,  A61L15/425 ,  A61L2300/41

Abstract: A porous dressing is provided. The porous dressing includes a polymeric layer, a pharmaceutically active ingredient and a metal oxide. The polymeric layer has a porosity and a bio-compatibility, and the pharmaceutically active ingredient and the metal oxide distribute in one selected from a group consisting of in the polymeric layer, on a surface of the polymeric layer and a combination thereof.

Abstract translation: 提供多孔敷料。 多孔敷料包括聚合物层，药物活性成分和金属氧化物。 聚合物层具有孔隙率和生物相容性，并且药物活性成分和金属氧化物分布在聚合物层中的聚合物层，聚合物层的表面及其组合中的一个中。

公开(公告)号：US20090043235A1

公开(公告)日：2009-02-12

申请号：US12001291

申请日：2007-12-11

Applicant: Ching-Cheng Huang ,  Su-Huei Lai ,  Yung-Sheng Lin ,  Ting-Kai Leung

Inventor： Ching-Cheng Huang ,  Su-Huei Lai ,  Yung-Sheng Lin ,  Ting-Kai Leung

IPC: A61F13/02 ,  A61L15/16

CPC classification number: A61L15/18 ,  A61F13/0209 ,  A61F13/0213 ,  A61F13/022 ,  A61L15/22 ,  A61L15/44 ,  A61L2300/41 ,  A61L2300/608

Abstract: A composite dressing including a first polymeric layer, a second polymeric layer, a metal oxide, and a pharmaceutical active material is provided. The second polymeric layer is biocompatible and is disposed on a surface of the first polymeric layer. The metal oxide is distributed inside or on at least one surface of the first polymeric layer, while the pharmaceutical active material is distributed inside or on at least one surface of the second polymeric layer.

Abstract translation: 提供包括第一聚合物层，第二聚合物层，金属氧化物和药物活性材料的复合敷料。 第二聚合物层是生物相容的并且设置在第一聚合物层的表面上。 金属氧化物分布在第一聚合物层的内部或至少一个表面上，而药物活性物质分布在第二聚合物层的内部或至少一个表面上。

公开(公告)号：US12109669B2

公开(公告)日：2024-10-08

申请号：US17716081

申请日：2022-04-08

Applicant: Yung-Sheng Lin ,  Shih-Liang Huang

Inventor： Yung-Sheng Lin ,  Shih-Liang Huang

IPC: B25B13/50

CPC classification number: B25B13/505

Abstract: A pipe plier structure includes a first body, a second body, a pivot member, and a locking member. The first body is provided with multiple first teeth, an arc line, an axis, a first vertical line, a radius, a first angle, and a second angle. The second body is provided with multiple second teeth, multiple third teeth, a second vertical line, a first connecting line, a second connecting line, a third angle, a fourth angle, a concave face, a fifth angle, a sixth angle, a seventh angle, and an eighth angle. The pivot member is assembled with the first body and the second body. The locking member is assembled with the first body and the second body. The locking member provides an elastically restoring force to the first body and the second body after the second body is extended outward relative to the first body.

公开(公告)号：US08480945B2

公开(公告)日：2013-07-09

申请号：US12836318

申请日：2010-07-14

Applicant: Chih-Hui Yang ,  Keng-Shiang Huang ,  Yung-Sheng Lin

Inventor： Chih-Hui Yang ,  Keng-Shiang Huang ,  Yung-Sheng Lin

IPC: B29C47/00

CPC classification number: A61K9/5089 ,  A61K9/5036 ,  B05B5/082 ,  D01D5/0076

Abstract: An electrospinning manufacture for drug carriers is disclosed. The method comprises a preliminary step mixing a predetermined drug, an alginate, and a saline to obtain a mixture; an electric field establishing step providing a collection plate and an emitter filled with divalent cation agent and the mixture individually, wherein an electric field is applied to the collection plate and the emitter to form a voltage therebetween; and an electrospinning step sequentially dropping the mixture from the emitter into the divalent cation agent filled in the collection plate via the driving of the electric field, triggering a crosslinking-gelating reaction between the divalent cation and the alginate, wherein a plurality of gel particles is produced for a coating of the predetermined drug presenting a drug carrier performance.

Abstract translation: 公开了用于药物载体的静电纺丝制造。 该方法包括将预定药物，藻酸盐和盐水混合以获得混合物的预备步骤; 电场建立步骤，提供收集板和填充有二价阳离子剂的发射体和所述混合物，其中电场施加到收集板和发射极以在它们之间形成电压; 以及静电纺丝步骤，通过驱动电场，将混合物从发射体顺序滴落到填充在收集板中的二价阳离子剂中，引发二价阳离子和藻酸盐之间的交联凝胶化反应，其中多个凝胶颗粒为 产生用于呈现药物载体性能的预定药物的涂层。

公开(公告)号：US20110168940A1

公开(公告)日：2011-07-14

申请号：US12710374

申请日：2010-02-23

Applicant: YUNG-SHENG LIN ,  TING-KAI LEUNG ,  CHIEN-CHUNG CHEN ,  JIANN-SHIUN KAO

Inventor： YUNG-SHENG LIN ,  TING-KAI LEUNG ,  CHIEN-CHUNG CHEN ,  JIANN-SHIUN KAO

IPC: C09K3/00

CPC classification number: C04B35/01 ,  Y10T428/31612

Abstract: The present invention discloses a composition for enhancing evaporation of a solution and a method thereof. A far-infrared ray is released by a far-infrared releasing substance in the composition so as to induce evaporation of the solution. The far-infrared releasing substance may be ceramic minerals and mainly comprises 80˜99.9 wt % of oxide minerals including 60˜95 wt % of the aluminum oxide. The present invention can enhance evaporation of the solution by a simple physical method. Hence, the present invention not only promotes the application of the products but also reduces the pollutants generated by a chemical reaction, thereby achieving the object of protecting the environment from the pollution.

Abstract translation: 本发明公开了一种用于增强溶液蒸发的组合物及其方法。 远红外线由组合物中的远红外线释放物质释放，以引起溶液的蒸发。 远红外线释放物质可以是陶瓷矿物质，主要含有80〜99.9重量％的氧化物矿物质，包括60〜95重量％的氧化铝。 本发明可以通过简单的物理方法增强溶液的蒸发。 因此，本发明不仅促进了产品的应用，而且还减少了化学反应产生的污染物，从而达到了保护环境免受污染的目的。

公开(公告)号：US20100047310A1

公开(公告)日：2010-02-25

申请号：US12458526

申请日：2009-07-15

Applicant: Chien-Chung CHEN ,  Jeng-Chang YANG ,  Suhan LI ,  En-Sheng KE ,  Yung-Sheng LIN

Inventor： Chien-Chung CHEN ,  Jeng-Chang YANG ,  Suhan LI ,  En-Sheng KE ,  Yung-Sheng LIN

IPC: A61F2/04 ,  C12N5/06 ,  A61F2/02 ,  B29C47/00

CPC classification number: A61L27/58 ,  A61B17/1128 ,  A61L27/383 ,  A61L27/3878 ,  A61L27/48 ,  A61L2430/32 ,  D01D5/0069 ,  D01D5/24

Abstract: Disclosed is a bio-electrospinning technique for preparing a cell-containing, oriented, continuous tubular scaffold, made of biodegradable polymer, designed for use as a nerve guide conduit (NGC) in nerve regeneration. With a coaxial spinneret, the PC-12 cell medium solution was co-electrospun into a core of tubular fibers, with PLA on the outer shell. The resulted fibers' morphology was characterized via SEM and optical microscopy, and following structural characteristics were found: 1. the larger, hollow fibers had diameters in tenth of microns and wall thicknesses around few microns, 2. an orientation in a preferred direction with the aid of a high-rotating collection device. The fluorescent PC12 cells embedded within the scaffold were cultured and nerve growth factor was added. We observed cells could not only survive the process, but also sustain their viability by undergoing differentiation process, extending neurite along the micro tubular scaffold in the desired direction. All these results demonstrate its potential application for advanced NGC.

Abstract translation: 公开了一种生物电纺丝技术，用于制备由可生物降解的聚合物制成的含细胞定向的连续管状支架，设计用于神经再生中的神经导管（NGC）。 使用同轴喷丝头，将PC-12细胞培养基溶液共同电纺丝成管状纤维的核心，PLA在外壳上。 通过SEM和光学显微镜对所得纤维的形态进行了表征，并发现了以下结构特征：1.较大的中空纤维的直径为十分之一微米，壁厚约为几微米，2.优选方向的取向为 辅助高旋转收集装置。 培养嵌入支架内的荧光PC12细胞，加入神经生长因子。 我们观察到细胞不仅可以在该过程中存活，而且通过进行分化过程维持其活力，沿着所需方向沿着微管状支架延伸神经突。 所有这些结果表明其潜在应用于先进的NGC。