Bicyclic heterocycles as cannabinoid receptor modulators
    1.
    发明申请
    Bicyclic heterocycles as cannabinoid receptor modulators 有权
    双环杂环作为大麻素受体调节剂

    公开(公告)号:US20060154955A1

    公开(公告)日:2006-07-13

    申请号:US11330540

    申请日:2006-01-12

    IPC分类号: C07D471/02 A61K31/4745

    CPC分类号: C07D471/04

    摘要: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I: including all pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R3a, R4, n, Y and Z are described herein.

    摘要翻译: 本申请描述了根据式I的化合物,包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物和使用根据式I的化合物的治疗方法,其单独和与一种或多种另外的 治疗剂。 化合物具有通式I:包括所有药学上可接受的盐和立体异构体,R 1,R 2,R 3,R 3, 3a,R 4,n,Y和Z在本文中描述。

    BICYCLIC HETEROCYCLES AS CANNABINOID-1 RECEPTOR MODULATORS
    2.
    发明申请
    BICYCLIC HETEROCYCLES AS CANNABINOID-1 RECEPTOR MODULATORS 有权
    作为CANNABINOID-1受体调节剂的双相异构体

    公开(公告)号:US20100048612A1

    公开(公告)日:2010-02-25

    申请号:US12609436

    申请日:2009-10-30

    IPC分类号: A61K31/437 C07D471/04

    CPC分类号: C07D471/04 C07D487/04

    摘要: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formula: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein A, B, R1, R2, R3 and R8 are described herein.

    摘要翻译: 本申请描述了根据式I的化合物,包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物和使用根据式I的化合物的治疗方法,其单独和与一种或多种另外的 治疗剂。 该化合物具有以下通式:包括所有前药,溶剂化物,药学上可接受的盐和立体异构体,其中A,B,R 1,R 2,R 3和R 8在本文中描述。

    Bicyclic heterocycles as cannabinoid-1 receptor modulators
    3.
    发明申请
    Bicyclic heterocycles as cannabinoid-1 receptor modulators 有权
    双环杂环作为大麻素-1受体调节剂

    公开(公告)号:US20060287324A1

    公开(公告)日:2006-12-21

    申请号:US11455039

    申请日:2006-06-16

    CPC分类号: C07D471/04 C07D487/04

    摘要: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formula: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein A, B, R1, R2, R3 and R8 are described herein.

    摘要翻译: 本申请描述了根据式I的化合物,包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物和使用根据式I的化合物的治疗方法,其单独和与一种或多种另外的 治疗剂。 所述化合物具有以下通式:包括所有前药,溶剂化物,药学上可接受的盐和立体异构体,其中A,B,R 1,R 2,R 3 本文描述了本文和/或 8。

    Bicyclic heterocycles as cannabinoid receptor modulators
    4.
    发明申请
    Bicyclic heterocycles as cannabinoid receptor modulators 有权
    双环杂环作为大麻素受体调节剂

    公开(公告)号:US20060155126A1

    公开(公告)日:2006-07-13

    申请号:US11330541

    申请日:2006-01-12

    IPC分类号: C07D471/02 C07D487/02

    CPC分类号: C07D471/04

    摘要: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I: including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R3a, R4, A, B, n, Y and Z are described herein.

    摘要翻译: 本申请描述了根据式I的化合物,包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物和使用根据式I的化合物的治疗方法,其单独和与一种或多种另外的 治疗剂。 该化合物具有通式I:包括所有前药,药学上可接受的盐和立体异构体,R 1,R 2,R 3,R 3, 本文描述了SUP,3a,R 4,A,B,n,Y和Z。

    Bicyclic heterocycles as cannabinoind-1 receptor modulators
    6.
    发明申请
    Bicyclic heterocycles as cannabinoind-1 receptor modulators 有权
    双环杂环作为大麻素-1受体调节剂

    公开(公告)号:US20060287322A1

    公开(公告)日:2006-12-21

    申请号:US11455045

    申请日:2006-06-16

    CPC分类号: C07D487/04

    摘要: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formulas I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formulas: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein B, R1, R2, R3 and x are described herein.

    摘要翻译: 本申请描述了根据式I的化合物,包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物和使用根据式I的化合物单独治疗并与一种或多种另外的组合的治疗方法 治疗剂。 该化合物具有以下通式:包括所有前药,溶剂化物,药学上可接受的盐和立体异构体,其中B,R 1,R 2,R 3, SUP>和x。

    Bicyclic heterocycles as cannabinoid receptor modulators
    8.
    发明申请
    Bicyclic heterocycles as cannabinoid receptor modulators 有权
    双环杂环作为大麻素受体调节剂

    公开(公告)号:US20060154956A1

    公开(公告)日:2006-07-13

    申请号:US11330656

    申请日:2006-01-12

    IPC分类号: C07D471/02 A61K31/4745

    摘要: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I: including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R3a, R4, A, B, b, n, W, X, Y and Z are described herein.

    摘要翻译: 本申请描述了根据式I的化合物,包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物和使用根据式I的化合物的治疗方法,其单独和与一种或多种另外的 治疗剂。 该化合物具有通式I:包括所有前药,药学上可接受的盐和立体异构体,R 1,R 2,R 3,R 3, 本文描述了SUP,3a,R 4,A,B,b,n,W,X​​,Y和Z。

    Bicyclic heterocycles as cannabinoid-1 receptor modulators
    9.
    发明授权
    Bicyclic heterocycles as cannabinoid-1 receptor modulators 有权
    双环杂环作为大麻素-1受体调节剂

    公开(公告)号:US07632837B2

    公开(公告)日:2009-12-15

    申请号:US11455039

    申请日:2006-06-16

    IPC分类号: C07D487/04 A61K31/5025

    CPC分类号: C07D471/04 C07D487/04

    摘要: The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the following general formula: including all prodrugs, solvates, pharmaceutically acceptable salts and stereoisomers, wherein A, B, R1, R2, R3 and R8 are described herein.

    摘要翻译: 本申请描述了根据式I的化合物,包含至少一种根据式I的化合物和任选的一种或多种另外的治疗剂的药物组合物和使用根据式I的化合物的治疗方法,其单独和与一种或多种另外的 治疗剂。 该化合物具有以下通式:包括所有前药,溶剂化物,药学上可接受的盐和立体异构体,其中A,B,R 1,R 2,R 3和R 8在本文中描述。