公开(公告)号：US08720496B2

公开(公告)日：2014-05-13

申请号：US12939272

申请日：2010-11-04

申请人： Christoph Huwiler ,  Florian Kuehni ,  Gerald Studer ,  Martin Wyss ,  Ulrich Haueter ,  David Teutsch

发明人： Christoph Huwiler ,  Florian Kuehni ,  Gerald Studer ,  Martin Wyss ,  Ulrich Haueter ,  David Teutsch

IPC分类号： B65B3/14

CPC分类号： B65B3/14 ,  A61J1/10 ,  A61J1/2075 ,  A61J1/2089 ,  A61M5/14244 ,  A61M5/38 ,  A61M2039/1077 ,  A61M2039/224 ,  A61M2209/045

摘要： A device, kit, and method for transferring a liquid medicament from a supply container to a flexible reservoir container are disclosed. The device may comprise a compartment unit and an adapter unit. The compartment unit may have a sealingly closable chamber, arranged for housing the flexible reservoir container and for being fluidly connected with a pump mechanism. The adapter unit may have at least one transfer passage for transferring liquid from a supply container connected to the adapter unit to the flexible reservoir container, and a separator arranged in the transfer passage for separating gas bubbles from a liquid streaming through the transfer passage. The separator may be fluidly connected to the chamber.

摘要翻译： 公开了一种用于将液体药物从供应容器转移到柔性贮存器容器的装置，试剂盒和方法。 该装置可以包括隔室单元和适配器单元。 隔室单元可以具有可密封关闭的室，其布置成容纳柔性储存容器并且与泵机构流体连接。 适配器单元可以具有至少一个传送通道，用于将液体从连接到适配器单元的供应容器传送到柔性容器容器，以及布置在传送通道中的分离器，用于将气泡与通过传送通道流出的液体分离。 分离器可以流体地连接到室。

公开(公告)号：US20110108158A1

公开(公告)日：2011-05-12

申请号：US12939272

申请日：2010-11-04

申请人： Christoph Huwiler ,  Florian Kuehni ,  Gerald Studer ,  Martin Wyss ,  Ulrich Haueter ,  David Teutsch

发明人： Christoph Huwiler ,  Florian Kuehni ,  Gerald Studer ,  Martin Wyss ,  Ulrich Haueter ,  David Teutsch

IPC分类号： B65B31/02

CPC分类号： B65B3/14 ,  A61J1/10 ,  A61J1/2075 ,  A61J1/2089 ,  A61M5/14244 ,  A61M5/38 ,  A61M2039/1077 ,  A61M2039/224 ,  A61M2209/045

摘要： A device, kit, and method for transferring a liquid medicament from a supply container to a flexible reservoir container are disclosed. The device may comprise a compartment unit and an adapter unit. The compartment unit may have a sealingly closable chamber, arranged for housing the flexible reservoir container and for being fluidly connected with a pump mechanism. The adapter unit may have at least one transfer passage for transferring liquid from a supply container connected to the adapter unit to the flexible reservoir container, and a separator arranged in the transfer passage for separating gas bubbles from a liquid streaming through the transfer passage. The separator may be fluidly connected to the chamber.

摘要翻译： 公开了一种用于将液体药物从供应容器转移到柔性贮存器容器的装置，试剂盒和方法。 该装置可以包括隔室单元和适配器单元。 隔室单元可以具有可密封关闭的室，其布置成容纳柔性储存容器并且与泵机构流体连接。 适配器单元可以具有至少一个传送通道，用于将液体从连接到适配器单元的供应容器传送到柔性容器容器，以及布置在传送通道中的分离器，用于将气泡与通过传送通道流出的液体分离。 分离器可以流体地连接到室。

公开(公告)号：US08500700B2

公开(公告)日：2013-08-06

申请号：US13046022

申请日：2011-03-11

申请人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

发明人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

IPC分类号： A61M5/00

CPC分类号： A61M5/14216 ,  A61M5/16804 ,  A61M5/16809

摘要： A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.

公开(公告)号：US20130165899A1

公开(公告)日：2013-06-27

申请号：US13788641

申请日：2013-03-07

申请人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

发明人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

IPC分类号： A61M5/168

CPC分类号： A61M5/14216 ,  A61M5/16804 ,  A61M5/16809

摘要： A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.

摘要翻译： 公开了一种用于移动式输液装置的计量单元和操作方法。 计量单元包括固定构件，可移动构件和柱塞。 可动构件和固定构件一起制成充气阀和排出阀。 柱塞至少部分地位于可移动构件的计量腔中，并且可移动构件适于选择性地联接和解耦驱动单元，使得通过操作驱动单元，可动构件与驱动联接 单元，可移动构件与柱塞一起移动以沿着位移轴线保持柱塞相对于可动构件的位置，并且通过使可动构件与驱动单元脱离而操作驱动单元，柱塞位移 被保持。

公开(公告)号：US08469930B2

公开(公告)日：2013-06-25

申请号：US13162028

申请日：2011-06-16

申请人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

发明人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

IPC分类号： A61M5/00

CPC分类号： A61M5/14216 ,  A61M5/16804 ,  A61M5/16809

摘要： A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.

公开(公告)号：US20110224644A1

公开(公告)日：2011-09-15

申请号：US13046022

申请日：2011-03-11

申请人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

发明人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

IPC分类号： A61M5/168

CPC分类号： A61M5/14216 ,  A61M5/16804 ,  A61M5/16809

摘要： A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.

摘要翻译： 公开了一种用于移动式输液装置的计量单元和操作方法。 计量单元包括固定构件，可移动构件和柱塞。 可动构件和固定构件一起制成充气阀和排出阀。 柱塞至少部分地位于可移动构件的计量腔中，并且可移动构件适于选择性地联接和解耦驱动单元，使得通过操作驱动单元，可动构件与驱动联接 单元，可移动构件与柱塞一起移动以沿着位移轴线保持柱塞相对于可动构件的位置，并且通过使可动构件与驱动单元脱离而操作驱动单元，柱塞位移 被保持。

公开(公告)号：US20110245781A1

公开(公告)日：2011-10-06

申请号：US13162028

申请日：2011-06-16

申请人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

发明人： Ulrich Haueter ,  Martin Wyss ,  Florian Kuehni

IPC分类号： A61M5/168 ,  B67D7/16

CPC分类号： A61M5/14216 ,  A61M5/16804 ,  A61M5/16809

摘要： A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.

摘要翻译： 公开了一种用于移动式输液装置的计量单元和操作方法。 计量单元包括固定构件，可移动构件和柱塞。 可动构件和固定构件一起制成充气阀和排出阀。 柱塞至少部分地位于可移动构件的计量腔中，并且可移动构件适于选择性地联接和解耦驱动单元，使得通过操作驱动单元，可动构件与驱动联接 单元，可移动构件与柱塞一起移动以沿着位移轴线保持柱塞相对于可动构件的位置，并且通过使可动构件与驱动单元脱离而操作驱动单元，柱塞位移 被保持。

公开(公告)号：US08602067B2

公开(公告)日：2013-12-10

申请号：US12792138

申请日：2010-06-02

申请人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

发明人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

IPC分类号： B65B31/04 ,  A61J1/00 ,  A61M5/142

CPC分类号： B65B31/025 ,  A61J1/10 ,  A61J1/20 ,  A61M5/14216 ,  A61M2209/045

摘要： A device for filling a flexible container and a method thereof are disclosed. The device may include a pressurizing chamber and an evacuation chamber. A first displacement piston is sealingly and slideably arranged within the pressurizing chamber to define an inner volume within the pressurizing chamber that is fluidly connected to a pressurizing conduit. A second displacement piston is sealingly and slideably arranged within the evacuation chamber to define an inner volume within the evacuation chamber that is fluidly connected to an evacuation conduit. A reservoir adapter is fluidly connected to the pressurizing conduit and connects to a liquid reservoir. A container adapter is fluidly connected to the evacuation conduit and connects with a flexible container. A transfer conduit is fluidly connected to the reservoir adapter and the container adapter. A valve fluidly connects the container adapter to the evacuation conduit or the transfer conduit.

摘要翻译： 公开了一种用于填充柔性容器的装置及其方法。 该装置可以包括加压室和排气室。 第一位移活塞被密封地和可滑动地布置在加压室内，以限定加压室内的内部容积，其流体地连接到加压管道。 第二位移活塞可密封地且可滑动地布置在排气室内，以限定抽空室内的内部容积，其流体地连接到排气管道。 储液器适配器流体地连接到加压管道并连接到液体储存器。 容器适配器流体地连接到排气管并与柔性容器连接。 转移导管流体连接到储存器适配器和容器适配器。 阀门将容器适配器流体地连接到排气管道或输送管道。

公开(公告)号：US20110132490A1

公开(公告)日：2011-06-09

申请号：US12792138

申请日：2010-06-02

申请人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

发明人： Florian Kuhni ,  Christoph Huwiler ,  Martin Wyss

IPC分类号： A61J1/00 ,  B65B3/17 ,  B65B31/00

CPC分类号： B65B31/025 ,  A61J1/10 ,  A61J1/20 ,  A61M5/14216 ,  A61M2209/045

摘要： A device for filling a flexible container and a method thereof are disclosed. The device may include a pressurizing chamber and an evacuation chamber. A first displacement piston is sealingly and slideably arranged within the pressurizing chamber to define an inner volume within the pressurizing chamber that is fluidly connected to a pressurizing conduit. A second displacement piston is sealingly and slideably arranged within the evacuation chamber to define an inner volume within the evacuation chamber that is fluidly connected to an evacuation conduit. A reservoir adapter is fluidly connected to the pressurizing conduit and connects to a liquid reservoir. A container adapter is fluidly connected to the evacuation conduit and connects with a flexible container. A transfer conduit is fluidly connected to the reservoir adapter and the container adapter. A valve fluidly connects the container adapter to the evacuation conduit or the transfer conduit.

摘要翻译： 公开了一种用于填充柔性容器的装置及其方法。 该装置可以包括加压室和排气室。 第一位移活塞被密封地和可滑动地布置在加压室内，以限定加压室内的内部容积，其流体地连接到加压管道。 第二位移活塞可密封地且可滑动地布置在排气室内，以限定抽空室内的内部容积，其流体地连接到排气管道。 储液器适配器流体地连接到加压管道并连接到液体储存器。 容器适配器流体地连接到排气管并与柔性容器连接。 转移导管流体连接到储存器适配器和容器适配器。 阀门将容器适配器流体地连接到排气管道或输送管道。

公开(公告)号：US09023009B2

公开(公告)日：2015-05-05

申请号：US13116348

申请日：2011-05-26

申请人： Martin Wyss ,  Florian Kühni ,  Ulrich Haueter

发明人： Martin Wyss ,  Florian Kühni ,  Ulrich Haueter

IPC分类号： A61B19/00 ,  A61M5/148 ,  A61J1/14 ,  A61M5/14 ,  A61M5/19 ,  A61J1/10

CPC分类号： A61M5/148 ,  A61J1/10 ,  A61J1/1475 ,  A61M5/141 ,  A61M5/1417 ,  A61M5/19 ,  A61M2209/045

摘要： A flexible container for storing a liquid medicament and a device for the automated release of the liquid medicament from the flexible container are disclosed. The flexible container includes a wall and an access opening. The wall of the flexible container comprises two sheets of flexible material sealed together such that a storage volume intended to contain the liquid medicament is defined. The access opening provides a fluid connection to a conduit system in fluid connection with the storage volume via a fluid channel arranged between the storage volume and the access opening, wherein the fluid channel is formed by a cavity arranged on at least one of the two sheets.

摘要翻译： 公开了一种用于储存液体药物的柔性容器和用于从柔性容器自动释放液体药物的装置。 柔性容器包括壁和通道开口。 柔性容器的壁包括两片密封在一起的柔性材料，从而限定了用于容纳液体药物的储存体积。 所述进入开口提供与通过设置在所述存储容积和所述进入开口之间的流体通道与所述存储容积流体连接的导管系统的流体连接，其中所述流体通道由布置在所述两个片材中的至少一个片材上的空腔形成 。