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1.发明授权Patch for screening and sensitization state of a subject with respect to an allergen and use thereof 有权关于受试者对变应原的筛选和致敏状态的补丁及其用途公开(公告)号：US07722897B2
公开(公告)日：2010-05-25
申请号：US10659566
申请日：2003-09-10
申请人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Stephane Benhamou , Pierre-Henri Benhamou
发明人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Stephane Benhamou , Pierre-Henri Benhamou
CPC分类号： A61K49/0006 , A61B10/0035
摘要： A patch comprises a support having electrostatic properties. The periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is directly covered with at least one biologically active substance in the form of particles. The particles remain in contact with the non-adhesive part of the support as a result of the electrostatic forces.
摘要翻译： 贴片包括具有静电特性的支持体。 支撑体的周边涂覆有粘合剂材料，并且载体的全部或部分非粘合剂表面直接用至少一种以颗粒形式的生物活性物质覆盖。 作为静电力的结果，颗粒保持与载体的非粘合部分接触。
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公开(公告)号：US07635488B2
公开(公告)日：2009-12-22
申请号：US11411531
申请日：2006-04-26
申请人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Pierre-Henri Benhamou , Jorge Ronco
发明人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Pierre-Henri Benhamou , Jorge Ronco
CPC分类号： A61B10/0035 , A61B2017/00526 , A61F2013/0296 , A61K49/0006
摘要： A patch comprising a support having electrostatic properties is provided wherein a periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is covered with at least one biologically active substance in the form of particles that is adhered to the non-adhesive part of the support by electrostatic forces.
摘要翻译： 提供了包括具有静电特性的支持体的贴片，其中支撑体的周边涂覆有粘合剂材料，并且支撑体的全部或部分非粘合表面被至少一种以颗粒形式的生物活性物质覆盖 其通过静电力粘附到支撑体的非粘合部分。
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公开(公告)号：US20070048361A1
公开(公告)日：2007-03-01
申请号：US11411531
申请日：2006-04-26
申请人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Pierre-Henri Benhamou , Jorge Ronco
发明人： Christophe Dupont , Bertrand Dupont , Pierre-Yves Vannerom , Pierre-Henri Benhamou , Jorge Ronco
CPC分类号： A61B10/0035 , A61B2017/00526 , A61F2013/0296 , A61K49/0006
摘要： A patch comprising a support having electrostatic properties is provided wherein a periphery of the support is coated with an adhesive material, and all or part of the non-adhesive surface of the support is covered with at least one biologically active substance in the form of particles that is adhered to the non-adhesive part of the support by electrostatic forces.
摘要翻译： 提供了包括具有静电特性的支持体的贴片，其中支撑体的周边涂覆有粘合剂材料，并且支撑体的全部或部分非粘合表面被至少一种以颗粒形式的生物活性物质覆盖 其通过静电力粘附到支撑体的非粘合部分。
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公开(公告)号：US20100260821A1
公开(公告)日：2010-10-14
申请号：US12745870
申请日：2008-12-03
CPC分类号： A61K39/35 , A61K9/0014 , A61K9/7007 , A61K9/7023 , A61K39/36 , A61K2039/54 , A61K2039/545
摘要： The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method, applicable to any type of allergens and of patients. The method of the invention is essentially non-invasive and does not require the use of adjuvants. Further, it may be easily applied and monitored by the actual patient.
摘要翻译： 本申请涉及一种使过敏患者脱敏的方法。 更具体地说，它涉及一种适用于任何类型的变应原和患者的表皮脱敏方法。 本发明的方法基本上是非侵入性的，并且不需要使用佐剂。 此外，它可以容易地被实际患者应用和监测。
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5.发明申请公开(公告)号：US20100136093A1
公开(公告)日：2010-06-03
申请号：US12628077
申请日：2009-11-30
CPC分类号： A61K39/35 , A61K9/0014 , A61K9/7007 , A61K9/7023 , A61K39/36 , A61K2039/54 , A61K2039/545
摘要： The present invention describes a new method for progressive desensitization of a subject to groundnut. More specifically, the invention relates to the immunotherapeutic method for increasing groundnut tolerance in an allergic subject using epicutaneous administration. The present invention is also relative to the use of a skin patch device for progressive desensitization of a subject to groundnut.
摘要翻译： 本发明描述了将受试者逐渐脱敏到花生的新方法。 更具体地，本发明涉及使用表皮给药来增加过敏性受试者中的花生耐受性的免疫治疗方法。 本发明还涉及皮肤贴片装置用于使受试者逐渐脱敏到花生的用途。
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6.发明授权公开(公告)号：US08202533B2
公开(公告)日：2012-06-19
申请号：US12628077
申请日：2009-11-30
CPC分类号： A61K39/35 , A61K9/0014 , A61K9/7007 , A61K9/7023 , A61K39/36 , A61K2039/54 , A61K2039/545
摘要： The present invention describes a new method for progressive desensitization of a subject to groundnut. More specifically, the invention relates to the immunotherapeutic method for increasing groundnut tolerance in an allergic subject using epicutaneous administration. The present invention is also relative to the use of a skin patch device for progressive desensitization of a subject to groundnut.
摘要翻译： 本发明描述了将受试者逐渐脱敏到花生的新方法。 更具体地，本发明涉及使用表皮给药来增加过敏性受试者中的花生耐受性的免疫治疗方法。 本发明还涉及皮肤贴片装置用于使受试者逐渐脱敏到花生的用途。
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公开(公告)号：US09539318B2
公开(公告)日：2017-01-10
申请号：US12745870
申请日：2008-12-03
CPC分类号： A61K39/35 , A61K9/0014 , A61K9/7007 , A61K9/7023 , A61K39/36 , A61K2039/54 , A61K2039/545
摘要： The present application relates to a method for desensitization of allergic patients. More specifically it relates to an epicutaneous desensitization method, applicable to any type of allergens and of patients. The method of the invention is essentially non-invasive and does not require the use of adjuvants. Further, it may be easily applied and monitored by the actual patient.
摘要翻译： 本申请涉及一种使过敏患者脱敏的方法。 更具体地说，它涉及一种适用于任何类型的变应原和患者的表皮脱敏方法。 本发明的方法基本上是非侵入性的，并且不需要使用佐剂。 此外，它可以容易地被实际患者应用和监测。
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公开(公告)号：US20090214621A1
公开(公告)日：2009-08-27
申请号：US11915926
申请日：2005-05-31
CPC分类号： A61B10/0035 , A61B17/205 , A61K9/703 , A61K9/7084
摘要： A dermal patch comprises a support having electrostatic properties, which is covered with or can be covered with a substance that is intended to be applied to the skin. The surface of the support that is in contact with the substance is provided with microreliefs.
摘要翻译： 皮肤贴剂包括具有静电特性的支持物，其被覆盖或可以被旨在施用于皮肤的物质覆盖。 与物质接触的载体的表面具有微裂纹。
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公开(公告)号：US20100297213A1
公开(公告)日：2010-11-25
申请号：US12863981
申请日：2009-01-23
CPC分类号： B05B5/087 , A61K9/14 , A61K9/7023 , A61K47/645 , B01F13/0076 , B05B5/0255 , B05B5/084 , B05B5/14 , B05D1/04 , B05D2252/04
摘要： The invention relates to patches and methods for manufacturing patches intended for skin application of a substance wherein the patch includes a conductive support, and a liquid formulation of the substance is deposited on the support of the patch by electrohydrodynamic spraying.
摘要翻译： 本发明涉及用于制造用于皮肤施用物质的贴片的贴片和方法，其中贴片包括导电支撑体，并且该物质的液体制剂通过电动液体喷涂沉积在贴片的支撑体上。
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公开(公告)号：US07781734B2
公开(公告)日：2010-08-24
申请号：US12165888
申请日：2008-07-01
IPC分类号： H01L25/00
CPC分类号： G01J5/20 , H04N5/33 , H04N5/335 , H04N5/3745
摘要： A thermal image sensor comprising at least: one pixel matrix, wherein each pixel comprises at least one bolometer and means of applying a voltage to the terminals of the bolometer, and a comparator connecting an output of the pixel matrix to an input of the means of applying the voltage to the terminals of the bolometer of each pixel, wherein said comparator is capable of making a comparison between the output signal of the pixel matrix and a reference value, wherein the value of the voltage at the terminals of the bolometer of each pixel is determined at least partially depending on the result of the comparison.
摘要翻译： 一种热图像传感器，至少包括：一个像素矩阵，其中每个像素包括至少一个测辐射热计和向测辐射热计的端子施加电压的装置，以及将像素矩阵的输出连接到 将电压施加到每个像素的测辐射热计的端子，其中所述比较器能够对像素矩阵的输出信号和参考值进行比较，其中每个像素的测辐射热计的端子处的电压值 至少部分地取决于比较的结果来确定。
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