公开(公告)号：US20070128087A1

公开(公告)日：2007-06-07

申请号：US10569114

申请日：2004-08-13

申请人： Christopher Cannizzaro ,  Urs Von Stockar

发明人： Christopher Cannizzaro ,  Urs Von Stockar

IPC分类号： C12Q1/00 ,  C12M1/00

CPC分类号： C12M37/00 ,  C12M33/04 ,  G01N1/18 ,  G01N35/08

摘要： The invention relates to a device for automated bioreactor sampling connected to a reactor comprising a sampler, at least one tube fluidly connecting said reactor with said sampler and a pump for pumping fluids from said reactor to said sampler and vice versa. Particularly simple and essentially dead volume-free sampling can be achieved by providing means for flushing at least parts of the tube with gas/sterile air between individual sampling steps. The invention furthermore relates to a method of operation of such a device.

摘要翻译： 本发明涉及一种用于自动生物反应器取样的装置，其连接到包括采样器的反应器，至少一个管子将所述反应器与所述采样器流体连接，并且泵将流体从所述反应器泵送到所述采样器，反之亦然。 可以通过提供在每个采样步骤之间用气体/无菌空气冲洗管的至少部分的装置来实现特别简单且基本上无死体积的取样。 本发明还涉及这种装置的操作方法。