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公开(公告)号：US20090005292A1
公开(公告)日：2009-01-01
申请号：US11718998
申请日：2005-11-11
申请人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , David Tumelty , Guy Lalonde , Palani Balu , Peter J. Schatz , William J. Dower , Anjan Chakrabarti , Yaohua S. Dong , Brian T. Frederick , Nicholas C. Wrighton
发明人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , David Tumelty , Guy Lalonde , Palani Balu , Peter J. Schatz , William J. Dower , Anjan Chakrabarti , Yaohua S. Dong , Brian T. Frederick , Nicholas C. Wrighton
CPC分类号： C07K14/505 , A61K38/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞生成相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US20120157660A1
公开(公告)日：2012-06-21
申请号：US12859204
申请日：2010-08-18
申请人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , David Tumelty , Guy Lalonde , Palani Balu , Peter J. Schatz , William J. Dower , Anjan Chakrabarti , Yaohua S. Dong , Brian T. Frederick , Nicholas C. Wrighton
发明人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , David Tumelty , Guy Lalonde , Palani Balu , Peter J. Schatz , William J. Dower , Anjan Chakrabarti , Yaohua S. Dong , Brian T. Frederick , Nicholas C. Wrighton
CPC分类号： C07K14/505 , A61K38/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞生成相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US20110282029A1
公开(公告)日：2011-11-17
申请号：US12965167
申请日：2010-12-10
申请人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , Yaohua S. Dong , David Tumelty , Guy Lalonde , Brian T. Frederick , Anjan Chakrabarti , Palani Balu , Peter J. Schatz , Nicholas C. Wrighton , William J. Dower
发明人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , Yaohua S. Dong , David Tumelty , Guy Lalonde , Brian T. Frederick , Anjan Chakrabarti , Palani Balu , Peter J. Schatz , Nicholas C. Wrighton , William J. Dower
CPC分类号： C07K14/505 , A61K38/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞生成相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US20130012685A1
公开(公告)日：2013-01-10
申请号：US13541420
申请日：2012-07-03
申请人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , Yaohua S. Dong , David Tumelty , Guy Lalonde , Brian T. Frederick , Anjan Chakrabarti , Palani Balu , Peter J. Schatz , Nicholas C. Wrighton , William J. Dower
发明人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , Yaohua S. Dong , David Tumelty , Guy Lalonde , Brian T. Frederick , Anjan Chakrabarti , Palani Balu , Peter J. Schatz , Nicholas C. Wrighton , William J. Dower
CPC分类号： C07K14/505 , A61K38/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞生成相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US20080108564A1
公开(公告)日：2008-05-08
申请号：US11735106
申请日：2007-04-13
申请人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , Yaohua S. Dong , David Tumelty , Guy Lalonde , Brian T. Frederick , Anjan Chakrabarti , Palani Balu , Peter J. Schatz , Nicholas C. Wrighton , William J. Dower
发明人： Christopher P. Holmes , Qun Yin , Genet Zemede , Ashok Bhandari , Yaohua S. Dong , David Tumelty , Guy Lalonde , Brian T. Frederick , Anjan Chakrabarti , Palani Balu , Peter J. Schatz , Nicholas C. Wrighton , William J. Dower
IPC分类号： A61K38/16 , C07K7/06 , C07K7/08 , C07K14/00 , A61P37/00 , A61P35/00 , A61P7/00 , A61K38/08 , A61K38/10
CPC分类号： C07K14/505 , A61K38/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞生成相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US08729030B2
公开(公告)日：2014-05-20
申请号：US12945687
申请日：2010-11-12
申请人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Palani Balu , Genet Zemede
发明人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Palani Balu , Genet Zemede
IPC分类号： C07K7/08 , C07K14/505 , A61K38/10 , C07K17/08
CPC分类号： C07K14/001 , A61K38/00 , A61K47/60 , C07K14/505 , C07K2319/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞产生相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US07855175B2
公开(公告)日：2010-12-21
申请号：US12171610
申请日：2008-07-11
申请人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Palani Balu , Genet Zemede
发明人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Palani Balu , Genet Zemede
CPC分类号： C07K14/001 , A61K38/00 , A61K47/60 , C07K14/505 , C07K2319/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞产生相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US07084245B2
公开(公告)日：2006-08-01
申请号：US10844968
申请日：2004-05-12
申请人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Balu Palani , Genet Zemede
发明人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Balu Palani , Genet Zemede
CPC分类号： C07K14/001 , A61K38/00 , A61K47/60 , C07K14/505 , C07K2319/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
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公开(公告)号：US20110245176A1
公开(公告)日：2011-10-06
申请号：US12945687
申请日：2010-11-12
申请人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Balu Palani , Genet Zemede
发明人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Balu Palani , Genet Zemede
CPC分类号： C07K14/001 , A61K38/00 , A61K47/60 , C07K14/505 , C07K2319/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞产生相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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公开(公告)号：US20090048166A1
公开(公告)日：2009-02-19
申请号：US12171610
申请日：2008-07-11
申请人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Balu Palani , Genet Zemede
发明人： Christopher P. Holmes , Qun Yin , Guy Lalonde , Peter J. Schatz , David Tumelty , Balu Palani , Genet Zemede
CPC分类号： C07K14/001 , A61K38/00 , A61K47/60 , C07K14/505 , C07K2319/00
摘要： The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention also relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.
摘要翻译： 本发明涉及作为促红细胞生成素受体（EPO-R）的激动剂的肽化合物。 本发明还涉及使用这种肽化合物治疗与不充分或有缺陷的红细胞产生相关的疾病的治疗方法。 还提供了包含本发明的肽化合物的药物组合物。
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