公开(公告)号：US20140017658A1

公开(公告)日：2014-01-16

申请号：US13545060

申请日：2012-07-10

申请人： Christopher P. STEINMAN ,  Jeffrey S. LOUIS ,  Rick W. WALKER ,  Evan D. SHAPIRO ,  Aaron R. FERBER ,  Rodney H. MONSON ,  John STARK ,  Ross LOCKWOOD

发明人： Christopher P. STEINMAN ,  Jeffrey S. LOUIS ,  Rick W. WALKER ,  Evan D. SHAPIRO ,  Aaron R. FERBER ,  Rodney H. MONSON ,  John STARK ,  Ross LOCKWOOD

IPC分类号： A01N1/02

CPC分类号： A01N1/0247 ,  A61M1/3627 ,  A61M1/3638 ,  A61M5/36

摘要： An apparatus for separating gas bubbles that may be entrained in perfusate flow prevents such bubbles from continuing downstream and entering an organ or tissue. The apparatus may include a chamber having a top wall, a bottom wall and side walls. The chamber may include an inlet configured to allow at least one of gas and liquid to enter the chamber, an air opening configured to allow at least gas to exit the chamber and a first liquid opening configured to allow at least liquid to exit the chamber. The apparatus may function as an accumulator that reduces or eliminates pulsatility of the liquid flow and pressure. The apparatus may include a minimum volume of gas, initially or through the accumulation of gas, such that flow and pressure fluctuations in the liquid are dampened or eliminated. The apparatus may include a sampling port in a wall of the chamber.

摘要翻译： 用于分离可能夹带在灌注液中的气泡的装置防止这种气泡继续下游并进入器官或组织。 该装置可以包括具有顶壁，底壁和侧壁的室。 腔室可以包括被配置为允许气体和液体中的至少一个进入腔室的入口，被配置为允许至少气体离开腔室的空气开口和被配置为允许至少液体离开腔室的第一液体开口。 该装置可以用作减少或消除液体流动和压力的脉动的蓄能器。 该装置可以包括最初体积的气体，最初或通过气体的积聚，使得液体中的流动和压力波动被抑制或消除。 该装置可以包括在该室的壁中的取样口。

公开(公告)号：US20140017663A1

公开(公告)日：2014-01-16

申请号：US13545442

申请日：2012-07-10

申请人： Christopher P. STEINMAN ,  John STARK ,  Joel C. HAGAN ,  Aaron R. FERBER ,  Rodney H. MONSON ,  Evan D. SHAPIRO

发明人： Christopher P. STEINMAN ,  John STARK ,  Joel C. HAGAN ,  Aaron R. FERBER ,  Rodney H. MONSON ,  Evan D. SHAPIRO

IPC分类号： A01N1/02

CPC分类号： A01N1/0247 ,  A01N1/0273

摘要： An apparatus for perfusing an organ or tissue includes a perfusion circuit configured to perfuse the organ or tissue; at least one shock and/or tilt detector such as an accelerometer; and a controller. The controller may be configured to control perfusion based upon a signal received from the accelerometer, which may include stopping and/or starting the perfusion based upon the signal. The controller may also or alternatively sense and/or record shocks experienced by the apparatus.

摘要翻译： 用于灌注器官或组织的装置包括构造成灌注器官或组织的灌注回路; 至少一个冲击和/或倾斜检测器，例如加速度计; 和控制器。 控制器可以被配置为基于从加速度计接收的信号来控制灌注，其可以包括基于该信号停止和/或启动灌注。 控制器还可以或者可选地感测和/或记录设备经历的冲击。