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公开(公告)号:US20140017658A1
公开(公告)日:2014-01-16
申请号:US13545060
申请日:2012-07-10
申请人: Christopher P. STEINMAN , Jeffrey S. LOUIS , Rick W. WALKER , Evan D. SHAPIRO , Aaron R. FERBER , Rodney H. MONSON , John STARK , Ross LOCKWOOD
发明人: Christopher P. STEINMAN , Jeffrey S. LOUIS , Rick W. WALKER , Evan D. SHAPIRO , Aaron R. FERBER , Rodney H. MONSON , John STARK , Ross LOCKWOOD
IPC分类号: A01N1/02
CPC分类号: A01N1/0247 , A61M1/3627 , A61M1/3638 , A61M5/36
摘要: An apparatus for separating gas bubbles that may be entrained in perfusate flow prevents such bubbles from continuing downstream and entering an organ or tissue. The apparatus may include a chamber having a top wall, a bottom wall and side walls. The chamber may include an inlet configured to allow at least one of gas and liquid to enter the chamber, an air opening configured to allow at least gas to exit the chamber and a first liquid opening configured to allow at least liquid to exit the chamber. The apparatus may function as an accumulator that reduces or eliminates pulsatility of the liquid flow and pressure. The apparatus may include a minimum volume of gas, initially or through the accumulation of gas, such that flow and pressure fluctuations in the liquid are dampened or eliminated. The apparatus may include a sampling port in a wall of the chamber.
摘要翻译: 用于分离可能夹带在灌注液中的气泡的装置防止这种气泡继续下游并进入器官或组织。 该装置可以包括具有顶壁,底壁和侧壁的室。 腔室可以包括被配置为允许气体和液体中的至少一个进入腔室的入口,被配置为允许至少气体离开腔室的空气开口和被配置为允许至少液体离开腔室的第一液体开口。 该装置可以用作减少或消除液体流动和压力的脉动的蓄能器。 该装置可以包括最初体积的气体,最初或通过气体的积聚,使得液体中的流动和压力波动被抑制或消除。 该装置可以包括在该室的壁中的取样口。
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公开(公告)号:US20140017770A1
公开(公告)日:2014-01-16
申请号:US13545321
申请日:2012-07-10
申请人: Christopher P. STEINMAN , Rick W. WALKER , Kirk C. PALMERTON , Jeffrey S. LOUIS , David PETTINATO , Matthew COPITHORNE , Brian L OTTS , Peter DEMUYLDER , James GUARRERA , Ben O. ARRINGTON
发明人: Christopher P. STEINMAN , Rick W. WALKER , Kirk C. PALMERTON , Jeffrey S. LOUIS , David PETTINATO , Matthew COPITHORNE , Brian L OTTS , Peter DEMUYLDER , James GUARRERA , Ben O. ARRINGTON
IPC分类号: A01N1/02
CPC分类号: A01N1/0247 , A01N1/0273
摘要: A perfusion apparatus includes a coolant container having a basin-receiving recess that is at least partly surrounded by an inner chamber; a basin that is shaped to fit within the basin-receiving recess of the coolant container; and a cradle that is shaped to accept an organ and fit within the basin. The basin-receiving recess of the coolant container, the basin and the cradle each have positioning elements that are oriented such that the cradle is keyed to fit within the basin and the basin is keyed to fit within the coolant container, each in a single predetermined orientation. The plurality of positioning elements on the basin may include a plurality of protrusions on an outer surface of the basin.
摘要翻译: 灌注装置包括:冷却剂容器,其具有至少部分地被内腔包围的盆容纳凹部; 成形为容纳在冷却剂容器的盆接收凹部内的盆; 和一个成形为接受器官并装配在盆内的摇篮。 冷却剂容器,盆和托架的盆容纳凹槽各自具有定位元件,其定位成使得支架被键合以配合在盆内,并且盆被键合以装配在冷却剂容器内,每个以单一预定 方向。 盆上的多个定位元件可以包括在盆的外表面上的多个突起。
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公开(公告)号:US20140017660A1
公开(公告)日:2014-01-16
申请号:US13545185
申请日:2012-07-10
申请人: Christopher P. STEINMAN , Jason A. BELTON , Kirk C. PALMERTON , Karl H. BEITZEL , Rick W. WALKER , Matthew COPITHORNE , Brian OTTS , James V. GUARRERA
发明人: Christopher P. STEINMAN , Jason A. BELTON , Kirk C. PALMERTON , Karl H. BEITZEL , Rick W. WALKER , Matthew COPITHORNE , Brian OTTS , James V. GUARRERA
CPC分类号: A01N1/0247 , A61B17/122 , A61B17/28 , A61B2017/00907 , A61B2017/00969 , A61B2017/2808
摘要: A cannula has a longitudinal base member having a first clamping end and a longitudinal arm member pivotally attached to the longitudinal base member and having a second clamping end, the cannula being in a closed position when the first and second clamping ends are brought together. A first clamp member is located at the first clamping end and has a first passage. A second clamp member is rotatably attached to the arm member at the second clamping end and has a second passage. The first and second passages form a combined passage when the clamp is in the closed position. The cannula may have a first locking member positioned on the arm member and a second locking member positioned on the base member. The first and second locking members interact with each other to lock the cannula in the closed position.
摘要翻译: 套管具有纵向底座构件,该纵向底座构件具有第一夹紧端和纵向臂构件,所述纵向臂构件可枢转地附接到纵向底座构件并且具有第二夹紧端,当第一和第二夹紧端部接合在一起时,套管处于关闭位置。 第一夹紧构件位于第一夹紧端并且具有第一通道。 第二夹紧构件在第二夹持端处可旋转地附接到臂构件并具有第二通道。 当夹具处于关闭位置时,第一和第二通道形成组合的通道。 套管可以具有定位在臂构件上的第一锁定构件和定位在基座构件上的第二锁定构件。 第一和第二锁定构件相互作用以将套管锁定在关闭位置。
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