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1.发明授权公开(公告)号：US09328172B2
公开(公告)日：2016-05-03
申请号：US12418519
申请日：2009-04-03
CPC分类号： C12N15/1065 , C07K16/2896 , C07K16/40 , C07K2317/56 , G06F19/00 , Y02A90/26
摘要： The invention is a methodology which makes it possible to select from a very large number of cells, a single cell or cells of interest and obtain specific information from those cells in a rapid and efficient manner. As an example of the methodology, a large number of antibody producing cells such as plasma cells are separated so that these individual antibody producing plasma cells are placed in individual wells. The cells are allowed to produce antibodies and the antibodies in the wells are then contacted with a protein bound to a solid surface such as a well top. The protein universally and specifically binds antibodies in the wells. The surface or well tray top includes addresses configured such that each address is specifically related to one of the individual wells containing a cell producing antibodies.
摘要翻译： 本发明是一种方法，其可以从非常大量的细胞，单个细胞或感兴趣的细胞中进行选择，并以快速和有效的方式从这些细胞获得特定的信息。 作为该方法的一个实例，分离大量抗体产生细胞如浆细胞，使得这些产生单个抗体的浆细胞放置在各个孔中。 使细胞产生抗体，然后将孔中的抗体与结合到固体表面如蛋白质顶部的蛋白质接触。 蛋白质通常和特异性结合孔中的抗体。 表面或井托盘顶部包括配置为使得每个地址与包含产生抗体的细胞的单个井中的一个具体相关的地址。
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2.发明申请公开(公告)号：US20110190148A1
公开(公告)日：2011-08-04
申请号：US12418519
申请日：2009-04-03
CPC分类号： C12N15/1065 , C07K16/2896 , C07K16/40 , C07K2317/56 , G06F19/00 , Y02A90/26
摘要： The invention is a methodology which makes it possible to select from a very large number of cells, a single cell or cells of interest and obtain specific information from those cells in a rapid and efficient manner. As an example of the methodology, a large number of antibody producing cells such as plasma cells are separated so that these individual antibody producing plasma cells are placed in individual wells. The cells are allowed to produce antibodies and the antibodies in the wells are then contacted with a protein bound to a solid surface such as a well top. The protein universally and specifically binds antibodies in the wells. The surface or well tray top includes addresses configured such that each address is specifically related to one of the individual wells containing a cell producing antibodies.
摘要翻译： 本发明是一种方法，其可以从非常大量的细胞，单个细胞或感兴趣的细胞中进行选择，并以快速和有效的方式从这些细胞获得特定的信息。 作为该方法的一个实例，分离大量抗体产生细胞如浆细胞，使得这些产生单个抗体的浆细胞放置在各个孔中。 使细胞产生抗体，然后将孔中的抗体与结合到固体表面如蛋白质顶部的蛋白质接触。 蛋白质通常和特异性结合孔中的抗体。 表面或井托盘顶部包括配置为使得每个地址与包含产生抗体的细胞的单个井中的一个具体相关的地址。
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公开(公告)号：US20080140557A1
公开(公告)日：2008-06-12
申请号：US11749407
申请日：2007-05-16
IPC分类号： G06Q30/00
摘要： A method and exchange for buying and selling rights in a legal contract or patent through an on-line exchange are disclosed. After obtaining a transfer of certain rights from the owner, and setting a transaction period during which the transferred rights can be bought and sold, the transferred rights are divided into fractions which can then be bought and sold, under buyer/seller exchange conditions. The bidding for fractions continues until a termination event occurs, which may be the expiration of the set transaction period or one of the participant buyer's acquiring a specified number of fractions of the transferred rights, in which case that participant can become the legal owner of the rights by acquiring all other ownership fractions in the rights at a predetermined price.
摘要翻译： 披露了通过在线交换在法律合同或专利中购买和出售权利的方法和交换。 在转让所有者的某些权利之后，设定转让权利可以买卖的交易期间，转让的权利分为几种，然后根据买卖双方交换条件进行买卖。 分数的招标持续到终止事件发生，可能是设定的交易期间到期或参与者买方获得指定数量的转移权限的一部分，在这种情况下，该参与者可以成为合法所有者 以预定价格获取权利中的所有其他所有权部分的权利。
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