公开(公告)号：US07127092B2

公开(公告)日：2006-10-24

申请号：US10258268

申请日：2001-04-16

申请人： Clifford R. Jack ,  Armando Manduca ,  Roger Grimm ,  Edward B. Welch

发明人： Clifford R. Jack ,  Armando Manduca ,  Roger Grimm ,  Edward B. Welch

IPC分类号： G06K9/00

CPC分类号： A61B5/055 ,  A61B5/7207 ,  G01R33/56509 ,  G01R33/5676 ,  Y10T436/24

摘要： A series of fMRI image frames are acquired along with interleaved navigator signals. The navigator signals are acquired while three orthogonal readout gradients are applied such that a spherical surface is sampled in k-space. The navigator signals are analyzed to measure subject rotational and translational motion during the scan.

摘要翻译： 一系列fMRI图像帧与交错导航信号一起被采集。 获取导航信号，同时施加三个正交读出梯度，使得球面在k空间中被采样。 分析导航信号以测量扫描期间的主体旋转和平移运动。

公开(公告)号：US20080262339A1

公开(公告)日：2008-10-23

申请号：US11631581

申请日：2005-06-28

申请人： Michael G. Garwood ,  Clifford R. Jack ,  Joseph F. Poduslo ,  Thomas M. Wengenack

发明人： Michael G. Garwood ,  Clifford R. Jack ,  Joseph F. Poduslo ,  Thomas M. Wengenack

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/4088 ,  A61B5/7285 ,  G01R33/5673

摘要： Amyloid plaque in the brain of a subject is imaged in an MRI system with or without the use of a contrast agent. Contrast is achieved using a spin-echo pulse sequence that is both respiratory gated and cardiac gated to reduce motion artifacts at the very high image resolution required to see plaque. A preparatory pulse sequence is used to insure longitudinal magnetization remains constant for all the acquired views even if the effective TR changes during the scan due to irregular breathing.

摘要翻译： 受试者脑中的淀粉样斑块在使用或不使用造影剂的MRI系统中成像。 使用呼吸门控和心脏门控的自旋回波脉冲序列来实现对比，以在看到斑块所需的非常高的图像分辨率下减少运动伪影。 准备脉冲序列用于确保纵向磁化对于所有获取的视图保持恒定，即使由于不规则呼吸而在扫描期间有效TR发生变化。

公开(公告)号：US07995825B2

公开(公告)日：2011-08-09

申请号：US10115334

申请日：2002-04-02

申请人： Clifford R. Jack ,  Peter C. O'Brien

发明人： Clifford R. Jack ,  Peter C. O'Brien

IPC分类号： G06K9/00

CPC分类号： G06T7/0012 ,  A61B5/055 ,  A61B5/7203 ,  A61B5/7264 ,  G01R33/56 ,  G01R33/5608 ,  G06T7/11 ,  G06T7/136 ,  G06T7/143 ,  G06T2207/10088 ,  G06T2207/20056 ,  G06T2207/30016 ,  G06T2207/30096

摘要： A method for classifying tissue in a magnetic resonance image, and particularly for measuring a volume of pathological tissue such as white tissue hyperintensity (leukoaraiosis) in the brain based on the segmentation of the intensity histogram of fluid attenuated inversion recovery (FLAIR) images is described. A magnetic resonance image of the brain of a subject is acquired, and a pixel intensity histogram is constructed from the image. A statistically-based regression analysis is applied to the histogram to determine upper and lower threshold values, which define different types of brain tissue, particularly normal brain, cerebral spinal fluid (CSF), or lesion.

摘要翻译： 描述了基于流体衰减反转恢复（FLAIR）图像的强度直方图的分割的用于对磁共振图像中的组织进行分类，特别是用于测量脑中的病理组织如白组织高信号（白细胞增多症）体积的方法。 。 获取对象的脑的磁共振图像，并从该图像构建像素强度直方图。 将基于统计学的回归分析应用于直方图以确定上限和下限阈值，其定义不同类型的脑组织，特别是正常脑，脑脊髓液（CSF）或病变。