公开(公告)号：US20170322210A1

公开(公告)日：2017-11-09

申请号：US15523792

申请日：2014-11-11

Applicant: Colgate-Palmolive Company

Inventor： Hans Stettler ,  Amy Russo RUSSO

IPC: G01N33/569 ,  C12M1/12 ,  C12Q1/18

CPC classification number: G01N33/56955 ,  C12M1/12 ,  C12Q1/18

Abstract: Disclosed is an in vitro oral biofilm model of interdental spaces including: a support, and a plurality of substratum pairs attached to the support, wherein an oral biofilm is capable of forming on the substratum pairs, wherein the substratum pairs each include a first member and a second member, and wherein the first member and the second member of each substratum pair are arranged to form a space interval between the first member and second member. Methods for assessing the formation of oral biofilms using the in vitro oral biofilm model and methods for testing agents, such as oral compositions, on biofilm reduction using the present model are also provided.