公开(公告)号：US20230138092A1

公开(公告)日：2023-05-04

申请号：US17974349

申请日：2022-10-26

Applicant: Colgate-Palmolive Company

Inventor： Robert D'AMBROGIO ,  Jean DENIS

IPC: A61K8/27 ,  A61K8/21 ,  A61K8/46 ,  A61Q11/02

Abstract: Described herein are oral care compositions comprising an effective amount of a stannous ion source and a taurate surfactant (e.g., sodium methyl cocoyl taurate). In one aspect the compositions of the disclosure can be used for the treatment or reduction of erosive tooth demineralization, gingivitis, plaque, and dental caries.

公开(公告)号：US20240173226A1

公开(公告)日：2024-05-30

申请号：US18515651

申请日：2023-11-21

Applicant: Colgate-Palmolive Company

Inventor： Robert D'AMBROGIO ,  Jean DENIS ,  Lauren EVANS

IPC: A61K8/27 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/44 ,  A61K8/73 ,  A61Q11/00

CPC classification number: A61K8/27 ,  A61K8/21 ,  A61K8/24 ,  A61K8/25 ,  A61K8/44 ,  A61K8/73 ,  A61K8/731 ,  A61Q11/00 ,  A61K2800/28 ,  A61K2800/48

Abstract: Described herein are oral care compositions comprising a surfactant system comprising an amino acid derived surfactant, and an amphoteric surfactant; a zinc salt; and a stannous ion source. Methods of making and using the same are also described.

公开(公告)号：US20230210733A1

公开(公告)日：2023-07-06

申请号：US18091571

申请日：2022-12-30

Applicant: Colgate-Palmolive Company

Inventor： Jean DENIS ,  Robert D'AMBROGIO ,  Guofeng XU

IPC: A61K8/27 ,  A61Q11/00 ,  A61K8/21

CPC classification number: A61K8/27 ,  A61Q11/00 ,  A61K8/21 ,  A61K2800/262 ,  A61K2800/28 ,  A61K2800/92

Abstract: This disclosure relates to translucent oral care compositions comprising one or more source(s) of zinc source and/or a stannous source. The translucent oral care composition can comprise one or more zinc and/or stannous ion source(s) in amounts effective to provide at least 28% soluble zinc and/or stannous as a fraction of the total zinc and/or stannous ion concentration in the composition; an abrasive (e.g., silica), wherein the abrasive has a refractive index of approximately 1.45 as measured in a 4% silica, 90% sorbitol/water solution; and an orally acceptable vehicle. Methods of using and of making these compositions is also disclosed herein.

公开(公告)号：US20240180800A1

公开(公告)日：2024-06-06

申请号：US18529347

申请日：2023-12-05

Applicant: Colgate-Palmolive Company

Inventor： Tatiana BRINZARI ,  Chi-Yuan CHENG ,  Zhigang HAO ,  Long PAN ,  Cristina CASTRO ,  Robert D'AMBROGIO ,  Jean DENIS

IPC: A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/34 ,  A61K8/55 ,  A61K8/67 ,  A61Q11/00

CPC classification number: A61K8/21 ,  A61K8/24 ,  A61K8/27 ,  A61K8/347 ,  A61K8/55 ,  A61K8/676 ,  A61Q11/00 ,  A61K2800/522

Abstract: Oral care compositions comprising a stannous ion source, tetrasodium pyrophosphate and an antioxidant, as well as to methods of using these compositions are disclosed herein. In some embodiments, the antioxidant is selected from ascorbyl phosphate and ascorbate.

公开(公告)号：US20210196588A1

公开(公告)日：2021-07-01

申请号：US17247618

申请日：2020-12-18

Applicant: Colgate-Palmolive Company

Inventor： Paul Thomson ,  Robert D'AMBROGIO ,  Jean DENIS ,  Guofeng XU

IPC: A61K8/27 ,  A61K8/19 ,  A61K8/60 ,  A61K8/34 ,  A61K8/88 ,  A61K8/73 ,  A61Q11/00

Abstract: The invention relates to oral care compositions comprising a first stannous ion source, a second stannous ion source, wherein the second stannous ion comprises stannous pyrophosphate, and a source of zinc selected from zinc oxide, zinc citrate, zinc lactate, and combinations thereof, and a humectant system comprising glycerin and sorbitol, and a thickening system, as well as to methods of using and making these compositions.

公开(公告)号：US20240269049A1

公开(公告)日：2024-08-15

申请号：US18436344

申请日：2024-02-08

Applicant: Colgate-Palmolive Company

Inventor： Robert D'AMBROGIO ,  Jean DENIS ,  Gokul GOVINDARAJU

IPC: A61K8/21 ,  A61K8/24 ,  A61K8/44 ,  A61K8/46 ,  A61K8/60 ,  A61K8/73 ,  A61Q11/00

CPC classification number: A61K8/21 ,  A61K8/24 ,  A61K8/44 ,  A61K8/466 ,  A61K8/602 ,  A61K8/731 ,  A61Q11/00 ,  A61K2800/30 ,  A61K2800/596

Abstract: Oral care compositions and methods of use thereof are disclosed herein. In accordance with some aspects, the oral care composition comprises from about 0.5 to about 9 wt. % of one or more surfactants; from about 0.3 to about 1 wt. % of one or more thickening agent; particles having a refractive index of from about 1.0 to about 2.5; a stannous ion source; a nitrate ion source; and a phosphate ion source, wherein the composition is substantially free of a titanium containing material, and all weight percentages are based on the total weight of the oral care composition.

公开(公告)号：US20240180798A1

公开(公告)日：2024-06-06

申请号：US18513925

申请日：2023-11-20

Applicant: Colgate-Palmolive Company

Inventor： Diana Liceth HENAO ADLEVANKIN ,  Jean DENIS ,  Lauren EVANS ,  Courtney Nicole HARRIS ,  Robert D'AMBROGIO ,  Gokul GOVINDARAJU

IPC: A61K8/21 ,  A61K8/19 ,  A61K8/24 ,  A61K8/44 ,  A61K8/46 ,  A61K8/60 ,  A61Q11/00

CPC classification number: A61K8/21 ,  A61K8/19 ,  A61K8/24 ,  A61K8/44 ,  A61K8/442 ,  A61K8/466 ,  A61K8/602 ,  A61Q11/00 ,  A61K2800/30

Abstract: Aspects of the invention are directed to oral care compositions. In accordance with an aspect, provided is an oral care composition having a surfactant system comprising at least one of: (i) a non-sulfate based anionic surfactant and an amphoteric surfactant, or (ii) a nonionic surfactant and an amino acid surfactant; a stannous ion source; a nitrate ion source; and a phosphate source.