公开(公告)号：US20230390164A1

公开(公告)日：2023-12-07

申请号：US18250384

申请日：2021-10-29

Applicant: Colgate-Palmolive Company

Inventor： Dailin CHEN ,  Shaopeng XU ,  Didi WU

IPC: A61K8/02 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/73

CPC classification number: A61K8/0204 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/731 ,  A61K2800/92 ,  A61K2800/30 ,  A61K2800/651

Abstract: Described herein are films comprising a particulate matter having a refractive index of from about 1.5 to about 2.0; a cellulosic material; and a polysaccharide; wherein the cellulosic material and the polysaccharide are present in a weight ratio of from about 2.2:1 to about 5:1; and wherein the film is substantially free of a titanium containing material. Compositions comprising same, and methods of using same are also described.

公开(公告)号：US20240050344A1

公开(公告)日：2024-02-15

申请号：US18549085

申请日：2021-03-11

Applicant: Colgate-Palmolive Company

Inventor： Ying YANG ,  Shaopeng XU ,  Guofeng XU ,  Harsh Mahendra TRIVEDI ,  James MASTERS ,  Dandan CHEN ,  Betty WON

IPC: A61K8/44 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/21

CPC classification number: A61K8/44 ,  A61K8/27 ,  A61Q11/00 ,  A61K8/21 ,  A61K2800/92

Abstract: Methods of increasing sIgA levels in an individual's oral cavity are disclosed. The methods comprise applying effective amounts of zinc oxide, zinc citrate, and arginine Methods of increasing the concentration of sIgA in the individual's mucosa pellicle in the oral cavity are disclosed. Methods of increasing phagocytotic activity of phagocytotic cells in the individual's oral cavity are also disclosed. In addition, methods of increasing levels of β-Defensin 1 in the individual's oral cavity are disclosed.

公开(公告)号：US20230190595A1

公开(公告)日：2023-06-22

申请号：US17765382

申请日：2022-03-03

Applicant: Colgate-Palmolive Company

Inventor： Lisa Marie MANUS ,  Jonghun LEE ,  Joseph Allan McKinnon STEELE ,  Shaopeng XU ,  Yuzhi DENG

IPC: A61K8/21 ,  A61K8/27 ,  A61K8/73 ,  A61K8/44 ,  A61Q11/00 ,  A61P31/04

CPC classification number: A61K8/21 ,  A61K8/27 ,  A61K8/735 ,  A61K8/442 ,  A61Q11/00 ,  A61P31/04

Abstract: This invention relates to oral care compositions comprising zinc oxide and zinc citrate, and hyaluronic acid or an alkali metal hyaluronate polymer having a molecular weight greater than 100,000 Da (e.g. from 300 kDa-700 kDa), as well as to methods of using and of making these compositions.

公开(公告)号：US20250064696A1

公开(公告)日：2025-02-27

申请号：US18724716

申请日：2022-12-21

Applicant: Colgate-Palmolive Company

Inventor： Yuwei CHEN ,  Shaopeng XU ,  Xu Qiang GAO

IPC: A61K8/34 ,  A61Q11/00

Abstract: Oral care compositions having antioxidant efficacy are disclosed. The oral care composition may include an orally acceptable vehicle and one or more phenolic compounds. The phenolic compounds may be capable of or configured to provide or improve antioxidant efficacy of the oral care composition. Methods for preparing the oral care compositions, methods for treating, preventing, or inhibiting one or more conditions of an oral cavity resulting from oxidative damage, and methods for scavenging one or more free radicals in an oral cavity are also disclosed.

公开(公告)号：US20220023180A1

公开(公告)日：2022-01-27

申请号：US17383934

申请日：2021-07-23

Applicant: Colgate-Palmolive Company

Inventor： Shuyun WU ,  Shaopeng XU ,  Yunran HUANG

IPC: A61K8/44 ,  A61K8/04 ,  A61K8/36 ,  A61K8/27 ,  A61K8/21 ,  A61K8/42 ,  A61Q11/00

Abstract: This invention relates to sodium lauryl sulfate (SLS)-free oral care compositions with improved foaming properties which comprise sodium lauroyl sarcosinate and a betaine, wherein the weight ratio of sodium lauroyl sarcosinate to the betaine is from 1:1.1 to 1:3.5, as well as to methods of using these compositions.