公开(公告)号：US11629223B2

公开(公告)日：2023-04-18

申请号：US17206400

申请日：2021-03-19

申请人： Colorado State University Research Foundation

发明人： Eugene Y. Chen ,  Xiaoyan Tang

IPC分类号： C08G63/08 ,  C08L67/04 ,  C08G63/82 ,  B01J31/22 ,  C08G63/664

摘要： Biodegradable polymers with advantageous physical and chemical properties are described, as well as methods for making such polymers. In one embodiment, a new chemical synthesis route to technologically important biodegradable poly(3-hydroxybutyrate) (P3HB) with high isotacticity and molecular weight required for a practical use is described. The new route can utilize racemic eight-membered cyclic diolide (rac-DL), meso-DL, or a rac-DL and meso-DL mixture, derived from bio-sourced dimethyl succinate, and enantiomeric (R,R)-DL and (S,S)-DL, optically resolved by metal-based catalysts. With a stereoselective racemic molecular catalyst, the ROP of rac-DL under ambient conditions produces rapidly P3HB with essentially perfect isotacticity ([mm]>99%), high crystallinity and melting temperature (Tm=171° C.), as well as high molecular weight and low dispersity (Mn=1.54×105 g/mol, Ð=1.01).

公开(公告)号：US20210206912A1

公开(公告)日：2021-07-08

申请号：US17206400

申请日：2021-03-19

申请人： Colorado State University Research Foundation

发明人： Eugene Y. Chen ,  Xiaoyan Tang

IPC分类号： C08G63/08 ,  C08G63/82 ,  C08L67/04 ,  B01J31/22

摘要： Biodegradable polymers with advantageous physical and chemical properties are described, as well as methods for making such polymers. In one embodiment, a new chemical synthesis route to technologically important biodegradable poly(3-hydroxybutyrate) (P3HB) with high isotacticity and molecular weight required for a practical use is described. The new route can utilize racemic eight-membered cyclic diolide (rac-DL), meso-DL, or a rac-DL and meso-DL mixture, derived from bio-sourced dimethyl succinate, and enantiomeric (R,R)-DL and (S,S)-DL, optically resolved by metal-based catalysts. With a stereoselective racemic molecular catalyst, the ROP of rac-DL under ambient conditions produces rapidly P3HB with essentially perfect isotacticity ([mm] >99%), high crystallinity and melting temperature (Tm=171° C.), as well as high molecular weight and low dispersity (Mn=1.54×105 g/mol, Ð=1.01).

公开(公告)号：US10954335B2

公开(公告)日：2021-03-23

申请号：US16246302

申请日：2019-01-11

申请人： Colorado State University Research Foundation

发明人： Eugene Y. Chen ,  Xiaoyan Tang

IPC分类号： C08G63/08 ,  C08L67/04 ,  C08G63/664 ,  C08G63/82 ,  B01J31/22

摘要： Biodegradable polymers with advantageous physical and chemical properties are described, as well as methods for making such polymers. In one embodiment, a new chemical synthesis route to technologically important biodegradable poly(3-hydroxybutyrate) (P3HB) with high isotacticity and molecular weight required for a practical use is described. The new route can utilize racemic eight-membered cyclic diolide (rac-DL), meso-DL, or a rac-DL and meso-DL mixture, derived from bio-sourced dimethyl succinate, and enantiomeric (R,R)-DL and (S,S)-DL, optically resolved by metal-based catalysts. With a stereoselective racemic molecular catalyst, the ROP of rac-DL under ambient conditions produces rapidly P3HB with essentially perfect isotacticity ([mm]>99%), high crystallinity and melting temperature (Tm=171° C.), as well as high molecular weight and low dispersity (Mn=1.54×105 g/mol, Ð=1.01).

公开(公告)号：US10364319B2

公开(公告)日：2019-07-30

申请号：US15565572

申请日：2016-04-11

申请人： Colorado State University Research Foundation

发明人： Eugene Y. Chen ,  Miao Hong ,  Xiaoyan Tang

IPC分类号： C08G63/08 ,  C08G63/82 ,  C08G69/14

摘要： The invention provides polymers of Formulas I-III, such as polyesters and unsaturated polyesters, and crosslinked and copolymerized polymers thereof. The invention also provides methods to catalytically ring-open five-membered rings such lactones, lactams, and thiolactones, as via ring-opening polymerization. The polymerization products are recyclable and can be depolymerized back to their monomer form via thermolysis and acid or base catalysis.