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    METHODS AND COMPOSITIONS FOR TREATING NEUROBLASTOMA IN A JUVENILE MAMMALIAN BODY
    4.
    发明申请
    METHODS AND COMPOSITIONS FOR TREATING NEUROBLASTOMA IN A JUVENILE MAMMALIAN BODY 有权

    公开(公告)号：US20220323450A1

    公开(公告)日：2022-10-13

    申请号：US17530138

    申请日：2021-11-18

    申请人： CorMedix Inc.

    发明人： Bruce Reidenberg ,  Robert DiLuccio

    IPC分类号： A61K31/549 ,  A61K9/00 ,  A61K9/14

    摘要： Neuroblastoma is a tumor primarily affecting children. The current standard of care is not curative except in the rare case of a surgically-resectable lesion, although very high survival rates have been documented for low-risk neuroblastoma and moderate-risk neuroblastoma. Taurolidine was developed as an anti-infective, but it has been found to have surprising oncolytic activity in cell cultures and now in a rodent cancer model. This invention relates to the use of taurolidine for the treatment of neuroblastoma in juvenile mammals.

    FIELD STERILIZER AND VASCULAR CONNECTOR KIT
    8.
    发明申请
    FIELD STERILIZER AND VASCULAR CONNECTOR KIT 审中-公开

    公开(公告)号：US20170274223A1

    公开(公告)日：2017-09-28

    申请号：US15471924

    申请日：2017-03-28

    申请人： CorMedix Inc.

    发明人： Bruce Reidenberg ,  Antony Pfaffle ,  Robert DiLuccio

    IPC分类号： A61N5/06 ,  A61M39/10 ,  A61M39/16

    摘要： Placement of a vascular access device (intravenous, intra-arterial and/or intra-osseous vascular access) in a non-sterile environment greatly increases the risk of infection via the vascular access device. This invention provides an approach for accomplishing sterilization of the site where vascular access will be attempted under non-sterile field conditions. In addition, this invention provides a sterile vascular connector pre-loaded with an antimicrobial, e.g., Taurolidine. Use of the vascular connector provides the antimicrobial concurrently with achieving vascular access, which limits the risk of infection despite access placement under non-sterile field conditions.