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    Method for producing fluorovinyl amide compound
    2.
    发明授权
    Method for producing fluorovinyl amide compound 有权

    公开(公告)号：US12281075B2

    公开(公告)日：2025-04-22

    申请号：US17299602

    申请日：2019-12-05

    Applicant: DAIKIN INDUSTRIES, LTD.

    Inventor： Naoyuki Hoshiya ,  Motoshi Matsui ,  Yosuke Kishikawa

    IPC: C07D211/76 ,  B01J23/44 ,  C07C231/12 ,  C07D207/27 ,  C07D209/44 ,  C07D263/22

    Abstract: An object of this disclosure provides a novel method for producing a fluorovinyl amide compound and the like. The object is achieved by a method for producing a compound represented by formula (1): wherein Rf is —F or fluoroalkyl, Ra1 is —H or an organic group, and Ra2 is —H or an organic group, or (i) Ra1 and Ra2, (ii) Ra1 and Rf, or (iii) Rf and Ra2, may be linked to each other, Rb1 is —H or an organic group, and Rb2 is —H or an organic group, or Rb1 and Rb2 may be linked together with their adjacent atoms to form a nitrogen-containing ring optionally having one or more substituents, the method comprising step A of reacting a compound represented by formula (2): wherein Rx is a leaving group, with a compound represented by formula (3) or a salt thereof: in the presence of a transition metal catalyst.

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