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    RADIATION TREATMENT PLANNING WITH MULTIPLE TARGET SUBSET OPTIMIZATION
    1.
    发明申请
    RADIATION TREATMENT PLANNING WITH MULTIPLE TARGET SUBSET OPTIMIZATION 审中-公开

    公开(公告)号：US20200346033A1

    公开(公告)日：2020-11-05

    申请号：US16870665

    申请日：2020-05-08

    申请人： DALHOUSIE UNIVERSITY

    发明人： Robert Lee MACDONALD ,  Alasdair SYME ,  Christopher G. THOMAS

    IPC分类号： A61N5/10

    摘要： Generating a plan for radiation treatment of multiple target volumes such as, for example, multiple brain tumors, involves optimizing a grouping of the target volumes into subsets and generating treatment plans for each subset. Resulting treatment plans may minimize radiation dose to tissues outside of the target volumes. A radiation treatment planning system may be configured to operate in this manner and to upload control signals which cause a radiation therapy device such as a linear accelerator to execute the radiation treatment plans.

    COORDINATED RADIOTHERAPY FOR PLURAL TARGETS
    2.
    发明申请
    COORDINATED RADIOTHERAPY FOR PLURAL TARGETS 审中-公开

    公开(公告)号：US20200164227A1

    公开(公告)日：2020-05-28

    申请号：US16615074

    申请日：2018-05-24

    申请人： Dalhousie University

    发明人： Robert Lee MACDONALD ,  Alasdair SYME ,  Christopher G. THOMAS

    IPC分类号： A61N5/10

    摘要： A radiation treatment planning system and method for generating plans to treat plural target volumes, each associated with a prescribed dose, does not require delivery of radiation to every target volume from every beam direction. Allowing target volumes to be omitted for some control points facilitates generation of treatment plans that deliver less radiation dose to non-target tissues by allowing beam shaping to more closely fit the remaining target volumes. Simulated annealing using an objective function may be applied to determine parameters such as the number of control points for which a target volume is not targeted.

    SYSTEMS AND METHODS FOR PLANNING AND CONTROLLING THE ROTATION OF A MULTILEAF COLLIMATOR FOR ARC THERAPY
    3.
    发明申请
    SYSTEMS AND METHODS FOR PLANNING AND CONTROLLING THE ROTATION OF A MULTILEAF COLLIMATOR FOR ARC THERAPY 审中-公开

    公开(公告)号：US20190030372A1

    公开(公告)日：2019-01-31

    申请号：US16083454

    申请日：2017-03-09

    申请人： DALHOUSIE UNIVERSITY

    发明人： Robert Lee MACDONALD ,  Alasdair SYME ,  Christopher G. THOMAS

    IPC分类号： A61N5/10

    摘要： Systems and methods are provided for determining an angular trajectory for dynamically rotating a multileaf collimator during arc therapy. According to various embodiments, a suitable collimator trajectory may be determined based on the reduction or minimization of a residual unblocked area residing between a planning target volume and leaves of the multileaf collimator in the beam's eye view over the set of control points corresponding to an arc therapy plan. Various example methods are provided for determining collimator trajectories based on whitespace reduction, and for providing quantitative measures of whitespace optimization associated with a given trajectory. In some embodiments, the whitespace may be calculated using terms that account for the overlap of a planning target volume with an organ at risk of exposure.