公开(公告)号：US20170131256A1

公开(公告)日：2017-05-11

申请号：US15410426

申请日：2017-01-19

Applicant: DALIAN UNIVERSITY OF TECHNOLOGY

Inventor： Yuhan ZHOU ,  Jingping QU ,  Xiaoliang DONG

IPC: G01N33/18 ,  G01N21/64 ,  C09K11/06 ,  C09B49/00

CPC classification number: G01N33/182 ,  C07F15/02 ,  C07F17/02 ,  C09B1/00 ,  C09B49/00 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1014 ,  C09K2211/187 ,  G01N21/643 ,  G01N2021/6439

Abstract: The present invention provides a carboxylate-bridged binuclear iron-sulfur clusters fluorescent probe having the structure of Formula I. The preparation method comprises the following steps: anthracenylmethanamine and p-methoxycarbonylphenyl isocyanate have an addition reaction to get a substitutional methyl benzoate, which is hydrolyzed to get a corresponding carboxylic acid; react the resulting carboxylic acid with alkali to get carboxylate, and then coordinate with binuclear iron precursor to obtain the fluorescent probe. Compared with the prior art, the invention firstly provides the carboxylate-bridged binuclear iron-sulfur clusters of metal complex which similar to the central structure of bio-enzyme. The metal complex, as a fluorescent probe, has good selectivity to the fluorinion detection. The fluorescence titration experiment is simple and easy to operate and the fluorescence changes are sensitive.