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公开(公告)号:US20110294779A1
公开(公告)日:2011-12-01
申请号:US13151310
申请日:2011-06-02
申请人: DANIELA ALBERATI , RUBÉN ALVAREZ SÁNCHEZ , KONRAD BLEICHER , ALEXANDER FLOHR , KATRIN GROEBKE ZBINDEN , MATTHIAS KOERNER , BERND KUHN , JENS-UWE PETERS , MARKUS RUDOLPH
发明人: DANIELA ALBERATI , RUBÉN ALVAREZ SÁNCHEZ , KONRAD BLEICHER , ALEXANDER FLOHR , KATRIN GROEBKE ZBINDEN , MATTHIAS KOERNER , BERND KUHN , JENS-UWE PETERS , MARKUS RUDOLPH
IPC分类号: A61K31/437 , A61K31/5377 , C07D519/00 , A61K31/4985 , A61K31/553 , A61P25/22 , A61K31/541 , A61P25/18 , A61P25/28 , A61P25/24 , A61P25/30 , C07D471/04 , A61K31/496
CPC分类号: C07D471/04 , A61K31/437 , A61K31/496 , A61K31/5025 , A61K31/5377 , A61K31/553 , C07D487/04
摘要: The invention is concerned with novel imidazopyridine derivatives of formula (I) wherein R1, R2, R3, R4, R5 and A are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used for the treatment of various diseases, including central nervous system disorders such as Alzheimer's disease, Parkinson's disease, and schizophrenia.